Articles producció científica> Medicina i Cirurgia

Canine sterile steroid-responsive lymphadenitis in 49 dogs

  • Identification data

    Identifier: imarina:6389564
    Authors:
    Ribas Latre AMcPartland ACain DWalker DBlack VVan Den Steen NWarman SBattersby IMurtagh KSilvestrini PBatchelor DTappin SW
    Abstract:
    © 2019 British Small Animal Veterinary Association Objectives: To report clinical and laboratory features, treatment responses and outcome in dogs diagnosed with sterile steroid-responsive lymphadenitis in the United Kingdom. Materials and Methods: Medical records of dogs diagnosed with sterile steroid-responsive lymphadenitis from 2009 to 2016 at six specialist referral centres were evaluated retrospectively. Results: The study included 49 dogs. Springer spaniels appeared to be over-represented (16 of 49 dogs). Young dogs (median age: 3 years and 9 months) and females (31 of 49) were frequently affected. Clinical presentation was variable, with pyrexia (39 of 49), lethargy (35 of 49) and anorexia (21 of 49) the most commonly reported clinical signs. Lymph node cytology or histopathology demonstrated neutrophilic, pyogranulomatous, granulomatous or necrotising lymphadenitis without a detectable underlying cause in all cases. Because a sterile immune-mediated aetiology was suspected, all dogs received prednisolone, which was followed by rapid resolution of clinical signs and lymphadenopathy in most cases. Clinical Significance: Sterile steroid-responsive lymphadenitis should be considered in dogs with pyrexia of unknown origin with inflammatory lymphadenopathy if no underlying cause can be found and often responds well to immunosuppressive corticosteroid therapy.
  • Others:

    Author, as appears in the article.: Ribas Latre A; McPartland A; Cain D; Walker D; Black V; Van Den Steen N; Warman S; Battersby I; Murtagh K; Silvestrini P; Batchelor D; Tappin SW
    Department: Medicina i Cirurgia
    URV's Author/s: Ribas Latre, Aleix
    Abstract: © 2019 British Small Animal Veterinary Association Objectives: To report clinical and laboratory features, treatment responses and outcome in dogs diagnosed with sterile steroid-responsive lymphadenitis in the United Kingdom. Materials and Methods: Medical records of dogs diagnosed with sterile steroid-responsive lymphadenitis from 2009 to 2016 at six specialist referral centres were evaluated retrospectively. Results: The study included 49 dogs. Springer spaniels appeared to be over-represented (16 of 49 dogs). Young dogs (median age: 3 years and 9 months) and females (31 of 49) were frequently affected. Clinical presentation was variable, with pyrexia (39 of 49), lethargy (35 of 49) and anorexia (21 of 49) the most commonly reported clinical signs. Lymph node cytology or histopathology demonstrated neutrophilic, pyogranulomatous, granulomatous or necrotising lymphadenitis without a detectable underlying cause in all cases. Because a sterile immune-mediated aetiology was suspected, all dogs received prednisolone, which was followed by rapid resolution of clinical signs and lymphadenopathy in most cases. Clinical Significance: Sterile steroid-responsive lymphadenitis should be considered in dogs with pyrexia of unknown origin with inflammatory lymphadenopathy if no underlying cause can be found and often responds well to immunosuppressive corticosteroid therapy.
    Thematic Areas: Ciências ambientais Ciências biológicas iii General medicine Interdisciplinar Medicina ii Medicina iii Medicina veterinaria Small animals Veterinary sciences
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: aleix.ribas@urv.cat
    Record's date: 2023-02-19
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.12980
    Papper original source: Journal Of Small Animal Practice. 60 (5): 280-290
    APA: Ribas Latre A; McPartland A; Cain D; Walker D; Black V; Van Den Steen N; Warman S; Battersby I; Murtagh K; Silvestrini P; Batchelor D; Tappin SW (2019). Canine sterile steroid-responsive lymphadenitis in 49 dogs. Journal Of Small Animal Practice, 60(5), 280-290. DOI: 10.1111/jsap.12980
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1111/jsap.12980
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2019
    Publication Type: Journal Publications
  • Keywords:

    Small Animals,Veterinary Sciences
    Ciências ambientais
    Ciências biológicas iii
    General medicine
    Interdisciplinar
    Medicina ii
    Medicina iii
    Medicina veterinaria
    Small animals
    Veterinary sciences
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