Author, as appears in the article.: Muria-Subirats E; Clua-Espuny JL; Ballesta-Ors J; Lorman-Carbo B; Lechuga-Duran I; Fernández-Saez J; Pla-Farnos R; On Behalf Members Of Africat Group

Department: Medicina i Cirurgia

URV's Author/s: Ballesta Ors, Juan / Muria Subirats, Eulàlia / Pla Farnòs, Roger Jesús

Keywords: Stroke Score Risk assessment Mellitus Hypertensive Diabetes Cohort study Chronic diseases Chads(2) Atrial fibrillation

Abstract: (1) Background: The link between diabetes and hypertension is mutual and reciprocal, increasing the risks for the development of atrial fibrillation (AF). The main objective was to develop a prediction model for AF in a population with both diabetes and hypertension at five years of follow-up. (2) Methods: A multicenter and community-based cohort study was undertaken of 8237 hypertensive diabetic patients without AF between 1 January 2103 and 31 December 2017. Multivariate Cox proportional-hazards regression models were used to identify predictors AF and to stratify risk scores by quartiles. (3) Results: AF incidence was 10.5/1000 people/years (95% confidence interval (CI) 9.5-11.5), higher in men. The independent prognostic factors identified: age (hazard ratio (HR) 1.07 95% CI 1.05-1.09, p < 0.001), weight (HR 1.03 95% CI 1.02-1.04, p < 0.001), CHA2DS2VASc score (HR 1.57 95% CI 1.16-2.13, p = 0.003) and female gender (HR 0.55 95% CI 0.37-0.82, p = 0.004). Q4 (highest-risk group for AF) had the highest AF incidence, stroke and mortality, and the smallest number needed to screen to detect one case of AF. (4) Conclusions: Risk-based screening for AF should be used in high cardiovascular risk patients as the hypertensive diabetics, for treatment of modifiable cardiovascular risk, and monitoring AF detection.

Thematic Areas: Zootecnia / recursos pesqueiros Serviço social Saúde coletiva Química Public, environmental & occupational health Public health, environmental and occupational health Psicología Pollution Odontología Nutrição Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Health, toxicology and mutagenesis Geografía Geociências Farmacia Environmental studies Environmental sciences Ensino Engenharias ii Engenharias i Enfermagem Educação física Educação Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência da computação Biotecnología Biodiversidade Astronomia / física Administração pública e de empresas, ciências contábeis e turismo

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: rogerjesus.pla@urv.cat

Author identifier: 0000-0002-3727-8933

Record's date: 2023-08-01

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.mdpi.com/1660-4601/17/10/3491

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: International Journal Of Environmental Research And Public Health. 17 (10):

APA: Muria-Subirats E; Clua-Espuny JL; Ballesta-Ors J; Lorman-Carbo B; Lechuga-Duran I; Fernández-Saez J; Pla-Farnos R; On Behalf Members Of Africat Group (2020). Incidence and Risk Assessment for Atrial Fibrillation at 5 Years: Hypertensive Diabetic Retrospective Cohort. International Journal Of Environmental Research And Public Health, 17(10), -. DOI: 10.3390/ijerph17103491

Article's DOI: 10.3390/ijerph17103491

Entity: Universitat Rovira i Virgili

Journal publication year: 2020

Publication Type: Journal Publications