Author, as appears in the article.: Carles Nadal, Joan; Borrull, Francesc; Furton, Kenneth G; Kabir, Abuzar; Fontanals, Nuria; Maria Marce, Rosa
Department: Química Analítica i Química Orgànica
URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria / Nadal Lozano, Joan Carles
Keywords: Ultraviolet detection Transformation products Stir-bar Sol-gel Polar Pharmaceuticals Personal care products Nonsteroidal antiinflammatory drugs Mixed-mode ion-exchange Metabolites Environmental samples Combination Capsule phase microextraction Basic analytes Bar sorptive extraction Acidic analytes mixed-mode ion-exchange environmental samples capsule phase microextraction basic analytes acidic analytes
Abstract: © 2020 In addition to the diverse extraction techniques available, capsule phase microextraction (CPME), which uses a microextraction capsule (MEC), has recently been introduced as a sorptive-based sample preparation technique. In this study, two different MECs (MEC-[sbnd]C18/SAX and MEC-C18/SCX) based on mixed-mode ion-exchange technology were synthesized and evaluated for the selective extraction of a group of ionizable compounds, including acidic and basic analytes. A sulfonic acid was used as the cation-exchange group in MEC-C18/SCX, and a quaternary amine as the anion-exchange group in MEC-[sbnd]C18/SAX. The extraction parameters optimized were sample pH, elution solvent, sample/elution volume and extraction/elution time. The optimized CPME method followed by LC-MS/MS was used to determine the ionizable compounds in environmental water samples, including river water and effluent wastewater, with excellent selectivity and matrix effect values below -30% (except -33% for mephedrone) and apparent recovery results ranging from 40% to 69%, except for ibuprofen (< 35%) and atenolol (< 25%). The analytical method was validated for environmental water samples, and used in the analysis of several samples in which some of the target compounds were found at ng L-1 concentration levels.
Thematic Areas: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00219673
Author's mail: joancarles.nadal@estudiants.urv.cat joancarles.nadal@estudiants.urv.cat nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0021967320305732
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Chromatography a. 1625 (461295): 461295-
APA: Carles Nadal, Joan; Borrull, Francesc; Furton, Kenneth G; Kabir, Abuzar; Fontanals, Nuria; Maria Marce, Rosa (2020). Selective monitoring of acidic and basic compounds in environmental water by capsule phase microextraction using sol-gel mixed-mode sorbents followed by liquid chromatography-mass spectrometry in tandem. Journal Of Chromatography a, 1625(461295), 461295-. DOI: 10.1016/j.chroma.2020.461295
Article's DOI: 10.1016/j.chroma.2020.461295
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV