Author, as appears in the article.: Diaz-Lopez, Andres; Jardi, Cristina; Villalobos, Marcela; Serrat, Nuria; Basora, Josep; Arija, Victoria
Department: Medicina i Cirurgia; Ciències Mèdiques Bàsiques
URV's Author/s: Arija Val, Maria Victoria / Basora Gallisa, Josep / Díaz López, Andres / Jardí Piñana, Cristina
Keywords: Vitamin-d status; Vitamin d deficiency; Vitamin d; Style; Prevalence; Pregnancy complications; Pregnancy; Humans; Female; D deficiency; Cross-sectional studies; Blood; Birth; Adult; 25-hydroxyvitamin d status
Abstract: © 2020, The Author(s). The hypovitaminosis D epidemic is a global health problem. Our aim was to assess the prevalence and potential risk factors of hypovitaminosis D among pregnant women on the eastern Mediterranean coast. Cross-sectional analysis involved 793 healthy pregnant women (35.3 ± 5.0 years) participating in ECLIPSES, a multicenter randomized trial. Socio-demographic, obstetric, anthropometric, lifestyle, dietary variables and blood draw was collected in the first trimester. Vitamin D deficiency was identified in 50.2% and insufficiency in 30.3% of pregnant women. The mean vitamin D level in the overall sample was 33.9 nmol/L (SD, 17.0). Multivariable logistic regression analysis applying AIC-based backward selection identified excess weight during the 1st trimester (BMI ≥ 25 kg/m2) (OR = 1.950, 95% CI = 1.409, 2.699), Arab ethnic group/dark skin colour (OR = 4.005, 95% CI = 2.488, 6.447), winter/spring (OR = 4.319, 95% CI = 3.112, 5.994), and consumption of milk (OR = 0.754, 95% CI = 0.572, 0.993) and yogurt (OR = 0.635, 95% CI = 0.436, 0.922) as independent risk factors for vitamin D deficiency. All of these factors (except yogurt consumption) and physical activity were independently associated with vitamin D deficiency/insufficiency risk in the final multivariable model (all p < 0.05). All these factors and social class were the most important determinants of circulating 25(OH)D concentrations. Our results confirm a high prevalence of vitamin D deficiency and insufficiency among pregnant women from the eastern Mediterranean coast.
Thematic Areas: Zootecnia / recursos pesqueiros; Saúde coletiva; Química; Psicología; Odontología; Nutrição; Multidisciplinary sciences; Multidisciplinary; Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Materiais; Matemática / probabilidade e estatística; Letras / linguística; Interdisciplinar; Geografía; Geociências; Farmacia; Engenharias iv; Engenharias iii; Engenharias ii; Enfermagem; Educação física; Educação; Economia; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Ciência da computação; Biotecnología; Biodiversidade; Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: josep.basora@urv.cat; andres.diaz@urv.cat; cristina.jardi@urv.cat; josep.basora@urv.cat; victoria.arija@urv.cat
Record's date: 2025-02-19
Paper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.nature.com/articles/s41598-020-71980-1
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Scientific Reports. 10 (1): 15757-
APA: Diaz-Lopez, Andres; Jardi, Cristina; Villalobos, Marcela; Serrat, Nuria; Basora, Josep; Arija, Victoria (2020). Prevalence and risk factors of hypovitaminosis D in pregnant Spanish women. Scientific Reports, 10(1), 15757-. DOI: 10.1038/s41598-020-71980-1
Article's DOI: 10.1038/s41598-020-71980-1
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV