Author, as appears in the article.: Díaz-López A; Jardí C; Villalobos M; Serrat N; Basora J; Arija V

Department: Medicina i Cirurgia Ciències Mèdiques Bàsiques

URV's Author/s: Arija Val, Maria Victoria / Basora Gallisa, Josep / Díaz López, Andres / Jardí Piñana, Cristina

Keywords: Vitamin-d status Style D deficiency Blood Birth 25-hydroxyvitamin d status

Abstract: © 2020, The Author(s). The hypovitaminosis D epidemic is a global health problem. Our aim was to assess the prevalence and potential risk factors of hypovitaminosis D among pregnant women on the eastern Mediterranean coast. Cross-sectional analysis involved 793 healthy pregnant women (35.3 ± 5.0 years) participating in ECLIPSES, a multicenter randomized trial. Socio-demographic, obstetric, anthropometric, lifestyle, dietary variables and blood draw was collected in the first trimester. Vitamin D deficiency was identified in 50.2% and insufficiency in 30.3% of pregnant women. The mean vitamin D level in the overall sample was 33.9 nmol/L (SD, 17.0). Multivariable logistic regression analysis applying AIC-based backward selection identified excess weight during the 1st trimester (BMI ≥ 25 kg/m2) (OR = 1.950, 95% CI = 1.409, 2.699), Arab ethnic group/dark skin colour (OR = 4.005, 95% CI = 2.488, 6.447), winter/spring (OR = 4.319, 95% CI = 3.112, 5.994), and consumption of milk (OR = 0.754, 95% CI = 0.572, 0.993) and yogurt (OR = 0.635, 95% CI = 0.436, 0.922) as independent risk factors for vitamin D deficiency. All of these factors (except yogurt consumption) and physical activity were independently associated with vitamin D deficiency/insufficiency risk in the final multivariable model (all p < 0.05). All these factors and social class were the most important determinants of circulating 25(OH)D concentrations. Our results confirm a high prevalence of vitamin D deficiency and insufficiency among pregnant women from the eastern Mediterranean coast.

Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: cristina.jardi@urv.cat josep.basora@urv.cat andres.diaz@urv.cat victoria.arija@urv.cat josep.basora@urv.cat

Author identifier: 0000-0002-7946-1488 0000-0002-7500-5629 0000-0002-1758-0975

Record's date: 2023-02-23

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.nature.com/articles/s41598-020-71980-1

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Scientific Reports. 10 (1):

APA: Díaz-López A; Jardí C; Villalobos M; Serrat N; Basora J; Arija V (2020). Prevalence and risk factors of hypovitaminosis D in pregnant Spanish women. Scientific Reports, 10(1), -. DOI: 10.1038/s41598-020-71980-1

Article's DOI: 10.1038/s41598-020-71980-1

Entity: Universitat Rovira i Virgili

Journal publication year: 2020

Publication Type: Journal Publications