Author, as appears in the article.: Voltas N; Canals J; Hernández-Martínez C; Serrat N; Basora J; Arija V

Department: Psicologia

URV's Author/s: Arija Val, Maria Victoria / Basora Gallisa, Josep / Canals Sans, Josefa / Hernandez Martinez, Carmen / Voltas Moreso, Núria

Keywords: Vitamin d Risk Prenatal nutrition Pregnancy Overweight Outcomes Neurodevelopment Language Infant D deficiency Childhood Association

Abstract: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Vitamin D status during pregnancy is involved in numerous physiological processes, including brain development. In this study, we assess the association between vitamin D status during pregnancy and infant neurodevelopment (cognitive, language, and motor skills). From an initial sample of 793 women (mean age 30.6) recruited before the 12th week of pregnancy, 422 mother–infant pairs were followed up to a postpartum visit. Vitamin D levels were assessed in the first and third trimesters of pregnancy, and socio-demographic, nutritional, and psychological variables were collected. At 40 days postpartum, the Bayley Scales of Infant Development-III were administered to the infants and several obstetrical data were recorded. Independently from several confounding factors, deficient vitamin D levels in the first trimester of pregnancy (<30 nmol/L) predicted a worse performance in cognitive and language skills. Language performance worsened with lower vitamin D levels (<20 nmol/L). In the third trimester, this highly deficient level was also associated with lower motor skills. Vitamin D deficiency was therefore associated with worse neurodevelopmental outcomes. More studies are needed to determine specific recommendations with regard to vitamin D supplementation during pregnancy in order to promote an optimal course for pregnancy and optimal infant neurodevelopment.

Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: josep.basora@urv.cat nuria.voltas@urv.cat victoria.arija@urv.cat josefa.canals@urv.cat josep.basora@urv.cat carmen.hernandez@urv.cat

Author identifier: 0000-0001-8855-0282 0000-0002-1758-0975 0000-0002-6209-9558 0000-0001-6328-8679

Record's date: 2023-05-21

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.mdpi.com/2072-6643/12/10/3196

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Nutrients. 12 (10): 1-20

APA: Voltas N; Canals J; Hernández-Martínez C; Serrat N; Basora J; Arija V (2020). Effect of vitamin d status during pregnancy on infant neurodevelopment: The eclipses study. Nutrients, 12(10), 1-20. DOI: 10.3390/nu12103196

Article's DOI: 10.3390/nu12103196

Entity: Universitat Rovira i Virgili

Journal publication year: 2020

Publication Type: Journal Publications