Author, as appears in the article.: Voltas N; Canals J; Hernández-Martínez C; Serrat N; Basora J; Arija V
Department: Medicina i Cirurgia Ciències Mèdiques Bàsiques Psicologia
URV's Author/s: Arija Val, Maria Victoria / Basora Gallisa, Josep / Canals Sans, Josefa / Hernandez Martinez, Carmen / Voltas Moreso, Núria
Keywords: Association Childhood D deficiency Infant Language Neurodevelopment Outcomes Overweight Pregnancy Prenatal nutrition Risk Vitamin d
Abstract: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Vitamin D status during pregnancy is involved in numerous physiological processes, including brain development. In this study, we assess the association between vitamin D status during pregnancy and infant neurodevelopment (cognitive, language, and motor skills). From an initial sample of 793 women (mean age 30.6) recruited before the 12th week of pregnancy, 422 mother–infant pairs were followed up to a postpartum visit. Vitamin D levels were assessed in the first and third trimesters of pregnancy, and socio-demographic, nutritional, and psychological variables were collected. At 40 days postpartum, the Bayley Scales of Infant Development-III were administered to the infants and several obstetrical data were recorded. Independently from several confounding factors, deficient vitamin D levels in the first trimester of pregnancy (<30 nmol/L) predicted a worse performance in cognitive and language skills. Language performance worsened with lower vitamin D levels (<20 nmol/L). In the third trimester, this highly deficient level was also associated with lower motor skills. Vitamin D deficiency was therefore associated with worse neurodevelopmental outcomes. More studies are needed to determine specific recommendations with regard to vitamin D supplementation during pregnancy in order to promote an optimal course for pregnancy and optimal infant neurodevelopment.
Thematic Areas: Biotecnología Ciência de alimentos Ciências agrárias i Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Educação física Enfermagem Engenharias ii Engenharias iv Farmacia Food science Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Nutrição Nutrition & dietetics Nutrition and dietetics Planejamento urbano e regional / demografia Psicología Química Saúde coletiva Zootecnia / recursos pesqueiros
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: carmen.hernandez@urv.cat josep.basora@urv.cat josefa.canals@urv.cat victoria.arija@urv.cat nuria.voltas@urv.cat josep.basora@urv.cat
Author identifier: 0000-0001-6328-8679 0000-0002-6209-9558 0000-0002-1758-0975 0000-0001-8855-0282
Record's date: 2023-05-21
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/12/10/3196
Papper original source: Nutrients. 12 (10): 1-20
APA: Voltas N; Canals J; Hernández-Martínez C; Serrat N; Basora J; Arija V (2020). Effect of vitamin d status during pregnancy on infant neurodevelopment: The eclipses study. Nutrients, 12(10), 1-20. DOI: 10.3390/nu12103196
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.3390/nu12103196
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications