Author, as appears in the article.: Kozlowska, Justyna; Tylkowski, Bartosz; Stachowiak, Natalia; Prus-Walendziak, Weronika
Department: Enginyeria Química
URV's Author/s: Tylkowski, Bartosz
Keywords: Alginate Calendula officinalis flower extract Calendula officinalisflower extract Calendula-officinalis Encapsulation Gelatin Glycerol Hydration Mechanical-properties Microspheres Polymer films Proteins Skin barrier Sodium alginate Starch Transepidermal water loss
Abstract: Human skin has protective functions and it is a barrier that protects the interior of the body from harmful environmental factors and pathogen penetration. An important role of the skin is also to prevent the loss of water from the body and if the skin barrier is damaged, the amount of water emitted from the internal environment is increased. Therefore, it is crucial to recovery and maintenance of epidermal barrier integrity. The aim of the current work was to encapsulateCalendula officinalisflower extract in gelatin microspheres and then incorporation microspheres into thin polymeric films made from sodium alginate or mixture of sodium alginate and starch. Such materials may find applications in the cosmetic field for example in the preparation of masks for skin, according to theCalendula officinalisflower extract wide influence on skin condition. Thus, the release profile of this extract from the materials was tested under conditions corresponding to the skin (pH 5.4, 37 degrees C). The mechanical properties, surface free energy, and moisture content of obtained films were measured. To determine the barrier quality of the stratum corneum, transepidermal water loss (TEWL) and skin color measurements were performed. The loaded microspheres were successfully incorporated into polymeric films without affecting its useful properties. Although the values of Young's modulus and the moisture content were decreased after film modification by microspheres addition, the skin parameters were much better after application of films with microspheres. The results confirmed that obtained materials can be potentially used in cosmetics to improve the skin barrier quality.
Thematic Areas: Bioengineering Chemical engineering (miscellaneous) Ciências biológicas ii Engenharias ii Engineering, chemical Process chemistry and technology
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: bartosz.tylkowski@urv.cat
Author identifier: 0000-0002-4163-0178
Record's date: 2025-01-28
Paper version: info:eu-repo/semantics/publishedVersion
Paper original source: Processes. 8 (5): 530-
APA: Kozlowska, Justyna; Tylkowski, Bartosz; Stachowiak, Natalia; Prus-Walendziak, Weronika (2020). Controlling the Skin Barrier Quality through the Application of Polymeric Films Containing Microspheres with Encapsulated Plant Extract. Processes, 8(5), 530-. DOI: 10.3390/pr8050530
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV