Author, as appears in the article.: Prats-Uribe, Albert; Tobed, Marc; Miguel Villacampa, Jose; Aguero, Adriana; Garcia-Bastida, Clara; Ignacio Tato, Jose; Rodriganez, Laura; Duque Holguera, Victoria; Hernandez-Garcia, Estefania; Poletti, Daniel; Simonetti, Gabriela; Villarraga, Vanessa; Meler-Claramonte, Carla; Sanchez Barrueco, Alvaro; Chiesa-Estomba, Carlos; Casasayas, Maria; Parente-Arias, Pablo; Mata-Castro, Nieves; Rello, Jordi; Castro, Pedro; Prieto-Alhambra, Daniel; Vilaseca, Isabel; Xavier Aviles-Jurado, Francesc;TraqueoCOVID SEORL Grp
Department: Medicina i Cirurgia
URV's Author/s: Avilés Jurado, Francisco Javier / Meler Claramonte, Carla / Rello Condomines, Jordi
Keywords: Weaning Tracheostomy Sars-cov-2 Respiratory failure Intensive care Complications
Abstract: Background Optimal timing for tracheotomy for critically ill COVID-19 patients requiring invasive mechanical ventilation (IMV) is not established. Methods Multicenter prospective cohort including all COVID-19 patients admitted to intensive care units (ICUs) in 36 hospitals who required tracheotomy during first pandemic wave. With a target emulation trial framework, we studied the causal effects of early (7-10 days) versus late (>10 days) tracheotomy (LT) on time from tracheotomy to weaning, postoperative mortality, and tracheotomy complications. Results Of 696 patients, 20.4% received early tracheotomy (ET). ET was associated with faster weaning (hazard ratio [HR] [95% confidence interval, CI]: 1.25 [1.00-1.56]) without differences in mortality (HR [95% CI]: 0.85 [0.60-1.21]) or complications (adjusted rate ratio [95% CI]: 0.56 [0.23-1.33]). Conclusions ET had a similar or lower post-tracheotomy weaning time than LT, potentially shortening IMV and ICU stays, without changing complication or mortality rates in COVID-19 patients.
Thematic Areas: Surgery Saúde coletiva Otorhinolaryngology Odontología Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: carla.meler@urv.cat franciscojavier.aviles@urv.cat carla.meler@urv.cat
Author identifier: 0000-0003-2263-4306 0000-0001-5560-8097 0000-0003-2263-4306
Record's date: 2024-03-19
Papper version: info:eu-repo/semantics/submittedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/10.1002/hed.26863
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck. 43 (12): 3743-3756
APA: Prats-Uribe, Albert; Tobed, Marc; Miguel Villacampa, Jose; Aguero, Adriana; Garcia-Bastida, Clara; Ignacio Tato, Jose; Rodriganez, Laura; Duque Holgue (2021). Timing of elective tracheotomy and duration of mechanical ventilation among patients admitted to intensive care with severe COVID-19: A multicenter prospective cohort study. Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck, 43(12), 3743-3756. DOI: 10.1002/hed.26863
Article's DOI: 10.1002/hed.26863
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV