Articles producció científica> Medicina i Cirurgia

Timing of elective tracheotomy and duration of mechanical ventilation among patients admitted to intensive care with severe COVID-19: A multicenter prospective cohort study

  • Identification data

    Identifier: imarina:9229377
    Handle: https://hdl.handle.net/20.500.11797/imarina9229377
    Authors:
    Prats-Uribe, AlbertTobed, MarcMiguel Villacampa, JoseAguero, AdrianaGarcia-Bastida, ClaraIgnacio Tato, JoseRodriganez, LauraDuque Holguera, VictoriaHernandez-Garcia, EstefaniaPoletti, DanielSimonetti, GabrielaVillarraga, VanessaMeler-Claramonte, CarlaSanchez Barrueco, AlvaroChiesa-Estomba, CarlosCasasayas, MariaParente-Arias, PabloMata-Castro, NievesRello, JordiCastro, PedroPrieto-Alhambra, DanielVilaseca, IsabelXavier Aviles-Jurado, Francesc
    Abstract:
    Background Optimal timing for tracheotomy for critically ill COVID-19 patients requiring invasive mechanical ventilation (IMV) is not established. Methods Multicenter prospective cohort including all COVID-19 patients admitted to intensive care units (ICUs) in 36 hospitals who required tracheotomy during first pandemic wave. With a target emulation trial framework, we studied the causal effects of early (7-10 days) versus late (>10 days) tracheotomy (LT) on time from tracheotomy to weaning, postoperative mortality, and tracheotomy complications. Results Of 696 patients, 20.4% received early tracheotomy (ET). ET was associated with faster weaning (hazard ratio [HR] [95% confidence interval, CI]: 1.25 [1.00-1.56]) without differences in mortality (HR [95% CI]: 0.85 [0.60-1.21]) or complications (adjusted rate ratio [95% CI]: 0.56 [0.23-1.33]). Conclusions ET had a similar or lower post-tracheotomy weaning time than LT, potentially shortening IMV and ICU stays, without changing complication or mortality rates in COVID-19 patients.

  • Others:

    Author, as appears in the article.: Prats-Uribe, Albert; Tobed, Marc; Miguel Villacampa, Jose; Aguero, Adriana; Garcia-Bastida, Clara; Ignacio Tato, Jose; Rodriganez, Laura; Duque Holguera, Victoria; Hernandez-Garcia, Estefania; Poletti, Daniel; Simonetti, Gabriela; Villarraga, Vanessa; Meler-Claramonte, Carla; Sanchez Barrueco, Alvaro; Chiesa-Estomba, Carlos; Casasayas, Maria; Parente-Arias, Pablo; Mata-Castro, Nieves; Rello, Jordi; Castro, Pedro; Prieto-Alhambra, Daniel; Vilaseca, Isabel; Xavier Aviles-Jurado, Francesc
    Department: Medicina i Cirurgia
    URV's Author/s: Avilés Jurado, Francisco Javier / Meler Claramonte, Carla / Rello Condomines, Jordi
    Keywords: Weaning Tracheotomy Tracheostomy Sars-cov-2 Respiratory failure Respiration, artificial Prospective studies Intensive care units Intensive care Humans Critical care Covid-19 Complications
    Abstract: Background Optimal timing for tracheotomy for critically ill COVID-19 patients requiring invasive mechanical ventilation (IMV) is not established. Methods Multicenter prospective cohort including all COVID-19 patients admitted to intensive care units (ICUs) in 36 hospitals who required tracheotomy during first pandemic wave. With a target emulation trial framework, we studied the causal effects of early (7-10 days) versus late (>10 days) tracheotomy (LT) on time from tracheotomy to weaning, postoperative mortality, and tracheotomy complications. Results Of 696 patients, 20.4% received early tracheotomy (ET). ET was associated with faster weaning (hazard ratio [HR] [95% confidence interval, CI]: 1.25 [1.00-1.56]) without differences in mortality (HR [95% CI]: 0.85 [0.60-1.21]) or complications (adjusted rate ratio [95% CI]: 0.56 [0.23-1.33]). Conclusions ET had a similar or lower post-tracheotomy weaning time than LT, potentially shortening IMV and ICU stays, without changing complication or mortality rates in COVID-19 patients.
    Thematic Areas: Surgery Saúde coletiva Otorhinolaryngology Odontología Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: franciscojavier.aviles@urv.cat carla.meler@urv.cat
    Author identifier: 0000-0001-5560-8097 0000-0003-2263-4306
    Record's date: 2024-10-12
    Papper version: info:eu-repo/semantics/submittedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck. 43 (12): 3743-3756
    APA: Prats-Uribe, Albert; Tobed, Marc; Miguel Villacampa, Jose; Aguero, Adriana; Garcia-Bastida, Clara; Ignacio Tato, Jose; Rodriganez, Laura; Duque Holgue (2021). Timing of elective tracheotomy and duration of mechanical ventilation among patients admitted to intensive care with severe COVID-19: A multicenter prospective cohort study. Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck, 43(12), 3743-3756. DOI: 10.1002/hed.26863
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications

  • Keywords:

    Otorhinolaryngology,Surgery
    Weaning
    Tracheotomy
    Tracheostomy
    Sars-cov-2
    Respiratory failure
    Respiration, artificial
    Prospective studies
    Intensive care units
    Intensive care
    Humans
    Critical care
    Covid-19
    Complications
    Surgery
    Saúde coletiva
    Otorhinolaryngology
    Odontología
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Engenharias iv
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Biotecnología

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