Author, as appears in the article.: Aparicio, Estefania; Martin-Grau, Carla; Hernandez-Martinez, Carmen; Voltas, Nuria; Canals, Josefa; Arija, Victoria;
Department: Ciències Mèdiques Bàsiques Psicologia
URV's Author/s: Aparicio Llopis, Estefania / Arija Val, Maria Victoria / Canals Sans, Josefa / Hernandez Martinez, Carmen / Voltas Moreso, Núria
Keywords: Visual-acuity Third trimester pregnancy Stearic acid Saturated fatty acid Risk Pregnant woman Pregnancy Polyunsaturated fatty acid Plasma Patient monitoring Palmitoleic acid Palmitic acid Omega-6 Omega-3 Omega 6 fatty acid Omega 3 fatty acid Oleic acid Myristic acid Monounsaturated fatty acid Mass fragmentography Major clinical study Longitudinal study Linoleic acid Lauric acid Lactation Iron Icosapentaenoic acid Human Gestation period Gamma linolenic acid First trimester pregnancy Female Fatty acid status Fatty acid blood level Fatty acid analysis Epa Docosahexaenoic acid Dha Conversion Controlled study Cohort analysis Clinical feature Childhood Blood sampling Birth Article Arachidonic acid Alpha-linolenic acid Adult
Abstract: Background During pregnancy a high amount of fatty acids (FA) is necessary to meet foetus demands, which vary during gestation. The present study describes the changes in maternal fatty acid concentrations during pregnancy in a sample of pregnant women. Methods This is a longitudinal study of 479 pregnant women who were monitored from the first trimester to third trimester of pregnancy. Data on maternal characteristics were recorded and a serum sample was collected in each trimester. The fatty acid profile (saturated (SFA: total, lauric acid, myristic acid, palmitic acid, stearic acid), monounsaturated (MUFA: total, palmitoleic acid, oleic acid) and polyunsaturated fatty acids (PUFA: total omega-6 (n-6), linoleic acid, dihomo-gamma-linolenic acid, arachidonic acid (AA), total omega-3 (n-3), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA)) was analysed with a gas chromatography-mass spectrometry combination. Results From the first trimester to third trimester of pregnancy, a significant increase in total SFA, total MUFA and total n-6 PUFA was found. (p < 0.001). Nevertheless, the serum concentration of arachidonic acid (AA), eicosapentaenoic acid (EPA) and total n-3 PUFA decreased during gestation (p < 0.001). A statistically non-significant result was observed for the docosahexaenoic acid (DHA) serum concentration between the first and third trimesters of pregnancy. Significant correlations were observed between each total fatty acid concentrations of the first and third trimesters. Conclusion The circulating serum concentration of SFA, MUFA and n-6 PUFA increases during pregnancy, whereas essential fatty acids such as AA and EPA decrease, and DHA remains unchanged. Further research is necessary to understand the role played by FA throughout gestation.
Thematic Areas: Surgery Serviço social Saúde coletiva Odontología Obstetrics and gynecology Obstetrics & gynecology Nutrição Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Ensino Enfermagem Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: nuria.voltas@urv.cat carmen.hernandez@urv.cat josefa.canals@urv.cat victoria.arija@urv.cat
Author identifier: 0000-0001-8855-0282 0000-0001-6328-8679 0000-0002-6209-9558 0000-0002-1758-0975
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-021-04251-0
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Bmc Pregnancy And Childbirth. 21 (1):
APA: Aparicio, Estefania; Martin-Grau, Carla; Hernandez-Martinez, Carmen; Voltas, Nuria; Canals, Josefa; Arija, Victoria; (2021). Changes in fatty acid levels (saturated, monounsaturated and polyunsaturated) during pregnancy. Bmc Pregnancy And Childbirth, 21(1), -. DOI: 10.1186/s12884-021-04251-0
Article's DOI: 10.1186/s12884-021-04251-0
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications