Author, as appears in the article.: Aparicio, Estefania; Martin-Grau, Carla; Hernandez-Martinez, Carmen; Voltas, Nuria; Canals, Josefa; Arija, Victoria;
Department: Ciències Mèdiques Bàsiques Psicologia
URV's Author/s: Aparicio Llopis, Estefania / Arija Val, Maria Victoria / Canals Sans, Josefa / Hernandez Martinez, Carmen / Voltas Moreso, Núria
Keywords: Adult Alpha-linolenic acid Arachidonic acid Article Birth Blood sampling Childhood Clinical feature Cohort analysis Controlled study Conversion Dha Docosahexaenoic acid Epa Fatty acid analysis Fatty acid blood level Fatty acid status Female First trimester pregnancy Gamma linolenic acid Gestation period Human Icosapentaenoic acid Iron Lactation Lauric acid Linoleic acid Longitudinal study Major clinical study Mass fragmentography Monounsaturated fatty acid Myristic acid Oleic acid Omega 3 fatty acid Omega 6 fatty acid Omega-3 Omega-6 Palmitic acid Palmitoleic acid Patient monitoring Plasma Polyunsaturated fatty acid Pregnancy Pregnant woman Risk Saturated fatty acid Stearic acid Third trimester pregnancy Visual-acuity
Abstract: Background During pregnancy a high amount of fatty acids (FA) is necessary to meet foetus demands, which vary during gestation. The present study describes the changes in maternal fatty acid concentrations during pregnancy in a sample of pregnant women. Methods This is a longitudinal study of 479 pregnant women who were monitored from the first trimester to third trimester of pregnancy. Data on maternal characteristics were recorded and a serum sample was collected in each trimester. The fatty acid profile (saturated (SFA: total, lauric acid, myristic acid, palmitic acid, stearic acid), monounsaturated (MUFA: total, palmitoleic acid, oleic acid) and polyunsaturated fatty acids (PUFA: total omega-6 (n-6), linoleic acid, dihomo-gamma-linolenic acid, arachidonic acid (AA), total omega-3 (n-3), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA)) was analysed with a gas chromatography-mass spectrometry combination. Results From the first trimester to third trimester of pregnancy, a significant increase in total SFA, total MUFA and total n-6 PUFA was found. (p < 0.001). Nevertheless, the serum concentration of arachidonic acid (AA), eicosapentaenoic acid (EPA) and total n-3 PUFA decreased during gestation (p < 0.001). A statistically non-significant result was observed for the docosahexaenoic acid (DHA) serum concentration between the first and third trimesters of pregnancy. Significant correlations were observed between each total fatty acid concentrations of the first and third trimesters. Conclusion The circulating serum concentration of SFA, MUFA and n-6 PUFA increases during pregnancy, whereas essential fatty acids such as AA and EPA decrease, and DHA remains unchanged. Further research is necessary to understand the role played by FA throughout gestation.
Thematic Areas: Administração pública e de empresas, ciências contábeis e turismo Biotecnología Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Educação física Enfermagem Ensino Interdisciplinar Matemática / probabilidade e estatística Materiais Medicina i Medicina ii Medicina iii Nutrição Obstetrics & gynecology Obstetrics and gynecology Odontología Saúde coletiva Serviço social Surgery
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: carmen.hernandez@urv.cat josefa.canals@urv.cat victoria.arija@urv.cat nuria.voltas@urv.cat estefania.aparicio@urv.cat
Author identifier: 0000-0001-6328-8679 0000-0002-6209-9558 0000-0002-1758-0975 0000-0001-8855-0282 0000-0003-0542-0015
Record's date: 2023-02-23
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-021-04251-0
Papper original source: Bmc Pregnancy And Childbirth. 21 (1):
APA: Aparicio, Estefania; Martin-Grau, Carla; Hernandez-Martinez, Carmen; Voltas, Nuria; Canals, Josefa; Arija, Victoria; (2021). Changes in fatty acid levels (saturated, monounsaturated and polyunsaturated) during pregnancy. Bmc Pregnancy And Childbirth, 21(1), -. DOI: 10.1186/s12884-021-04251-0
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1186/s12884-021-04251-0
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV