Articles producció científica> Bioquímica i Biotecnologia

Adjusted morbidity groups and intracerebral haemorrhage: A retrospective primary care cohort study

  • Identification data

    Identifier: imarina:9242319
    Authors:
    Lorman-Carbo, BlancaClua-Espuny, Josep LluisMuria-Subirats, EulaliaBallesta-Ors, JuanGonzalez-Henares, Maria AntoniaPalleja-Millan, MeritxellMartin-Lujan, Francisco M
    Abstract:
    Background: Intracerebral haemorrhage rates are increasing among highly complex, elderly patients. The main objective of this study was to identify modifiable risk factors of intracerebral haemorrhage. Methods: Multicentre, retrospective, community-based cohort study was conducted, including patients in the Adjusted Morbidity Group 4 with no history of intracerebral haemorrhage. Cases were obtained from electronic clinical records of the Catalan Institute of Health and were followed up for five years. The primary outcome was the occurrence of intracerebral haemorrhage during the study period. Demographic, clinical and pharmacological variables were included. Logistic regression analyses were carried out to detect prognostic variables for intracerebral haemorrhage. Results: 4,686 subjects were included; 170 (3.6%) suffered an intracerebral haemorrhage (85.8/10,000 person–year [95% CI 85.4 to 86.2]). The HAS-BLED score for intracerebral haemorrhage risk detection obtained the best AUC (0.7) when used in the highest complexity level (cut-off point ?3). Associated independent risk factors were age ?80 years, high complexity and use of antiplatelet agents. Conclusions: The Adjusted Morbidity Group 4 is associated with a high risk of intracerebral haemorrhage, particularly for highly complex patients and the use of antiplatelet agents. The risk of bleeding in these patients must be closely monitored. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
  • Others:

    Author, as appears in the article.: Lorman-Carbo, Blanca; Clua-Espuny, Josep Lluis; Muria-Subirats, Eulalia; Ballesta-Ors, Juan; Gonzalez-Henares, Maria Antonia; Palleja-Millan, Meritxell; Martin-Lujan, Francisco M
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Ballesta Ors, Juan / Lorman Carbó, Blanca / Martín Lujan, Francisco Manuel
    Keywords: Retrospective studies Primary health care Multimorbidity Morbidity Intracranial hemorrhage Humans Cohort studies Chronicity Cerebral hemorrhage Cerebral haemorrhage Aged, 80 and over Aged trends risk-factors primary health care prevention people multimorbidity management ischemic-stroke guidelines disease chronicity atrial-fibrillation
    Abstract: Background: Intracerebral haemorrhage rates are increasing among highly complex, elderly patients. The main objective of this study was to identify modifiable risk factors of intracerebral haemorrhage. Methods: Multicentre, retrospective, community-based cohort study was conducted, including patients in the Adjusted Morbidity Group 4 with no history of intracerebral haemorrhage. Cases were obtained from electronic clinical records of the Catalan Institute of Health and were followed up for five years. The primary outcome was the occurrence of intracerebral haemorrhage during the study period. Demographic, clinical and pharmacological variables were included. Logistic regression analyses were carried out to detect prognostic variables for intracerebral haemorrhage. Results: 4,686 subjects were included; 170 (3.6%) suffered an intracerebral haemorrhage (85.8/10,000 person–year [95% CI 85.4 to 86.2]). The HAS-BLED score for intracerebral haemorrhage risk detection obtained the best AUC (0.7) when used in the highest complexity level (cut-off point ?3). Associated independent risk factors were age ?80 years, high complexity and use of antiplatelet agents. Conclusions: The Adjusted Morbidity Group 4 is associated with a high risk of intracerebral haemorrhage, particularly for highly complex patients and the use of antiplatelet agents. The risk of bleeding in these patients must be closely monitored. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
    Thematic Areas: Zootecnia / recursos pesqueiros Serviço social Saúde coletiva Química Public, environmental & occupational health Public health, environmental and occupational health Psicología Pollution Odontología Nutrição Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Health, toxicology and mutagenesis Geografía Geociências Farmacia Environmental studies Environmental sciences Ensino Engenharias ii Engenharias i Enfermagem Educação física Educação Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência da computação Biotecnología Biodiversidade Astronomia / física Administração pública e de empresas, ciências contábeis e turismo
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: blanca.lorman@estudiants.urv.cat paco.martin@urv.cat
    Author identifier: 0000-0003-0359-3588
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/1660-4601/18/24/13320
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: International Journal Of Environmental Research And Public Health. 18 (24): 13320-
    APA: Lorman-Carbo, Blanca; Clua-Espuny, Josep Lluis; Muria-Subirats, Eulalia; Ballesta-Ors, Juan; Gonzalez-Henares, Maria Antonia; Palleja-Millan, Meritxel (2021). Adjusted morbidity groups and intracerebral haemorrhage: A retrospective primary care cohort study. International Journal Of Environmental Research And Public Health, 18(24), 13320-. DOI: 10.3390/ijerph182413320
    Article's DOI: 10.3390/ijerph182413320
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Environmental Sciences,Health, Toxicology and Mutagenesis,Pollution,Public Health, Environmental and Occupational Health,Public, Environmental & Occupational Health
    Retrospective studies
    Primary health care
    Multimorbidity
    Morbidity
    Intracranial hemorrhage
    Humans
    Cohort studies
    Chronicity
    Cerebral hemorrhage
    Cerebral haemorrhage
    Aged, 80 and over
    Aged
    trends
    risk-factors
    primary health care
    prevention
    people
    multimorbidity
    management
    ischemic-stroke
    guidelines
    disease
    chronicity
    atrial-fibrillation
    Zootecnia / recursos pesqueiros
    Serviço social
    Saúde coletiva
    Química
    Public, environmental & occupational health
    Public health, environmental and occupational health
    Psicología
    Pollution
    Odontología
    Nutrição
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Health, toxicology and mutagenesis
    Geografía
    Geociências
    Farmacia
    Environmental studies
    Environmental sciences
    Ensino
    Engenharias ii
    Engenharias i
    Enfermagem
    Educação física
    Educação
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência da computação
    Biotecnología
    Biodiversidade
    Astronomia / física
    Administração pública e de empresas, ciências contábeis e turismo
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