Validation of an Algorithm for the Prediction of Diabetic Retinopathy in Type 1 Diabetic Patients in a Spanish Population

Identifier:  imarina:9247751

Handle: https://hdl.handle.net/20.500.11797/imarina9247751

Authors:  Romero-Aroca, P; Baget-Bernaldiz, M; Navarro-Gil, R; Feliu, A; Maarof, N; Moreno, A; Cristiano, J; Valls, A

Abstract:
The aim of the present study was to build a clinical decision support system (CDSS) that can predict the presence of diabetic retinopathy (DR) in type 1 diabetes (T1DM) patients. We built two versions of our CDSS to predict the presence of any-type DR and sight-threatening DR (STDR) in T1DM patients. The first version was trained using 324 T1DM and 826 T2DM patients. The second was trained with only the 324 T1DM patients. The first version achieved an accuracy (ACC) = 0.795, specificity (SP) = 83%, and sensitivity (S) = 65.7% to predict the presence of any-DR, and an ACC = 0.918, SP = 87.1% and S = 87.8% for STDR. The second model achieved ACC = 0.799, SP = 87.5% and S = 86.3% when predicting any-DR and ACC = 0.937, SP = 90.9% and S = 83.0% for STDR. The two models better predict STDR than any-DR in T1DM patients. We will need a larger sample to strengthen our results.