Author, as appears in the article.: Salto, Joan; Biosca, Maria; Pamies, Oscar; Dieguez, Montserrat;

Department: Química Física i Inorgànica

URV's Author/s: Biosca Brull, Maria / Diéguez Fernández, Montserrat

Keywords: Tricarbocycles Sesquiterpene Pauson-khand reactions Pauson-khand Metal-catalysis Ligands Design Cyclizations Cobalt Asymmetric-synthesis Allylic substitution

Abstract: A set of complex tricyclic compounds containing several functional groups and multiple stereogenic centers has been prepared in only two steps with excellent diastereo- and enantioselectivities. The synthesis takes advantage of the highly versatile and enantioselective Pd-catalyzed allylic substitution of simple cyclic allylic acetates or carbonates to form chiral 1,6-, 1,7- and 1,8-enynes, which are then diastereoselectively transformed to the corresponding cyclopentenone- and cyclobutene-based tricyclic compounds.

Thematic Areas: Química Organic chemistry Materiais Engenharias iv Engenharias ii Ciências biológicas ii Ciência de alimentos Chemistry, organic Chemistry, applied Catalysis Biodiversidade Astronomia / física

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: maria.biosca@urv.cat montserrat.dieguez@urv.cat

Author identifier: 0000-0002-9116-6318 0000-0002-8450-0656

Record's date: 2023-02-23

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/adsc.202200685

Papper original source: Advanced Synthesis & Catalysis. 364 (21): 3682-3689

APA: Salto, Joan; Biosca, Maria; Pamies, Oscar; Dieguez, Montserrat; (2022). Synthesis of Chiral, Fused Tricyclic Molecules by Sequential Metal-Catalyzed Reactions of Simple Substrates. Advanced Synthesis & Catalysis, 364(21), 3682-3689. DOI: 10.1002/adsc.202200685

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Article's DOI: 10.1002/adsc.202200685

Entity: Universitat Rovira i Virgili

Journal publication year: 2022

Publication Type: Journal Publications