Articles producció científicaQuímica Analítica i Química Orgànica

Direct and efficient glycosylation protocol for synthesizing ?-glycolipids: Application to the synthesis of KRN7000

  • Identification data

    Identifier:  imarina:9284764
    Handle: https://hdl.handle.net/20.500.11797/imarina9284764
    Authors:  Boutureira, O; Morales-Serna, JA; Díaz, Y; Matheu, MI; Castillón, S
    Abstract:
    Herein we describe a simple and practical protocol for accessing the biologically active galactosyl ceramide KRN7000 and other ?-glycolipids with excellent yield and stereoselectivity by using per-O-silylated galactosyl iodide and stannyl ethers as glycosylation partners. This direct glycosylation reaction reduces the overall number of steps and provides rapid access to biologically important ?-galactosyl ceramide derivatives. © Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

  • Others:

    Link to the original source: https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.200701228
    APA: Boutureira, O; Morales-Serna, JA; Díaz, Y; Matheu, MI; Castillón, S (2008). Direct and efficient glycosylation protocol for synthesizing ?-glycolipids: Application to the synthesis of KRN7000. European Journal Of Organic Chemistry, 2008(11), 1851-1854. DOI: 10.1002/ejoc.200701228
    Paper original source: European Journal Of Organic Chemistry. 2008 (11): 1851-1854
    Article's DOI: 10.1002/ejoc.200701228
    Journal publication year: 2008-04-01
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/acceptedVersion
    Record's date: 2026-05-09
    URV's Author/s: Boutureira Martín, Omar / Castillón Miranda, Sergio / Díaz Giménez, María Yolanda / Matheu Malpartida, María Isabel
    Department: Química Analítica i Química Orgànica
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    Author, as appears in the article.: Boutureira, O; Morales-Serna, JA; Díaz, Y; Matheu, MI; Castillón, S
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Thematic Areas: Physical and theoretical chemistry, Organic chemistry, Interdisciplinar, Chemistry, organic, Biotecnología, Astronomia / física
    Author's mail: sergio.castillon@urv.cat, sergio.castillon@urv.cat, omar.boutureira@urv.cat, omar.boutureira@urv.cat, yolanda.diaz@urv.cat, yolanda.diaz@urv.cat, yolanda.diaz@urv.cat, maribel.matheu@urv.cat, maribel.matheu@urv.cat

  • Keywords:

    Tin
    Synthesis
    Síntesis organica estereoselectiva
    Phytosphingosine
    Glycosylation
    Glycolipids
    Carbohidratos
    Chemistry
    Organic
    Organic Chemistry
    Physical and Theoretical Chemistry
    Interdisciplinar
    Biotecnología
    Astronomia / física

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