Articles producció científicaQuímica Analítica i Química Orgànica

Direct and efficient glycosylation protocol for synthesizing ?-glycolipids: Application to the synthesis of KRN7000

  • Identification data

    Identifier:  imarina:9284764
    Handle: https://hdl.handle.net/20.500.11797/imarina9284764
    Authors:  Boutureira, Omar; Antonio Morales-Serna, Jose; Diaz, Yolanda; Matheu, M Isabel; Castillon, Sergio
    Abstract:
    Herein we describe a simple and practical protocol for accessing the biologically active galactosyl ceramide KRN7000 and other ?-glycolipids with excellent yield and stereoselectivity by using per-O-silylated galactosyl iodide and stannyl ethers as glycosylation partners. This direct glycosylation reaction reduces the overall number of steps and provides rapid access to biologically important ?-galactosyl ceramide derivatives. © Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

  • Others:

    Link to the original source: https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.200701228
    APA: Boutureira, Omar; Antonio Morales-Serna, Jose; Diaz, Yolanda; Matheu, M Isabel; Castillon, Sergio (2008). Direct and efficient glycosylation protocol for synthesizing ?-glycolipids: Application to the synthesis of KRN7000. European Journal Of Organic Chemistry, 2008(11), 1851-1854. DOI: 10.1002/ejoc.200701228
    Paper original source: European Journal Of Organic Chemistry. 2008 (11): 1851-1854
    Article's DOI: 10.1002/ejoc.200701228
    Journal publication year: 2008
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/acceptedVersion
    Record's date: 2024-11-30
    URV's Author/s: Boutureira Martín, Omar / Castillón Miranda, Sergio / Díaz Giménez, María Yolanda / Matheu Malpartida, María Isabel
    Department: Química Analítica i Química Orgànica
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    Author, as appears in the article.: Boutureira, Omar; Antonio Morales-Serna, Jose; Diaz, Yolanda; Matheu, M Isabel; Castillon, Sergio
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Thematic Areas: Química, Physical and theoretical chemistry, Organic chemistry, Materiais, Interdisciplinar, Farmacia, Engenharias ii, Ciências biológicas iii, Ciências biológicas ii, Ciências agrárias i, Ciência de alimentos, Chemistry, organic, Biotecnología, Biodiversidade, Astronomia / física
    Author's mail: omar.boutureira@urv.cat, yolanda.diaz@urv.cat, maribel.matheu@urv.cat, sergio.castillon@urv.cat

  • Keywords:

    Tin
    Synthesis
    Síntesis organica estereoselectiva
    Phytosphingosine
    Glycosylation
    Glycolipids
    Carbohidratos
    Chemistry
    Organic
    Organic Chemistry
    Physical and Theoretical Chemistry
    Química
    Materiais
    Interdisciplinar
    Farmacia
    Engenharias ii
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biodiversidade
    Astronomia / física

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