Author, as appears in the article.: Miguens-Gomez, Alba; Sierra-Cruz, Marta; Segu, Helena; Beltran-Debon, Raul; Rodriguez-Gallego, Esther; Terra, Ximena; Teresa Blay, Maria; Maria Perez-Vendrell, Anna; Pinent, Montserrat; Ardevol, Anna
Department: Bioquímica i Biotecnologia
URV's Author/s: Ardévol Grau, Anna / Beltrán Debón, Raúl Alejandro / Blay Olivé, Maria Teresa / Miguéns Gómez, Alba / Pinent Armengol, Montserrat / Rodríguez Gallego, Esther / Segú Matamoros, Helena / Sierra Cruz, Marta / Terra Barbadora, Ximena
Keywords: Vitro digestion method Tenebrio Rats Meals Insecta Insect Gut Glucagon-like peptide 1 Ghrelin Food intake Female Enterohormones Eating Dietary protein Coleoptera Cattle Animals yellow mealworm release protein insect gut growth-performance glp-1 ghrelin food intake enterohormones enteroendocrine cells blood profiles
Abstract: BACKGROUND: It has been previously shown that acutely administered insect Alphitobius diaperinus protein increases food intake in rats and modifies the ex vivo enterohormone secretory profile differently than beef or almond proteins. In this study, we aimed to evaluate whether these effects could be maintained for a longer period and determine the underlying mechanisms. RESULTS: We administered two different insect species to rats for 26 days and measured food intake at different time points. Both insect species increased food intake in the first week, but the effect was later lost. Glucagon-like peptide 1 (GLP-1) and ghrelin were measured in plasma and ex vivo, and no chronic effects on their secretion or desensitization were found. Nevertheless, digested A. diaperinus acutely modified GLP-1 and ghrelin secretion ex vivo. CONCLUSION: Our results suggest that increases in food intake could be explained by a local ghrelin reduction acting in the small intestine. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Thematic Areas: Zootecnia / recursos pesqueiros Química Planejamento urbano e regional / demografia Nutrition and dietetics Nutrição Medicina veterinaria Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar General medicine Food science & technology Food science Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, applied Biotecnología Biotechnology Biodiversidade Astronomia / física Agronomy and crop science Agriculture, multidisciplinary Agriculture Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: alba.miguens@urv.cat helena.segu@urv.cat alba.miguens@urv.cat alba.miguens@urv.cat marta.sierra@estudiants.urv.cat marta.sierra@estudiants.urv.cat anna.ardevol@urv.cat ximena.terra@urv.cat mteresa.blay@urv.cat esther.rodriguez@urv.cat montserrat.pinent@urv.cat raul.beltran@urv.cat
Author identifier: 0000-0003-0156-7538 0000-0003-1043-5844 0000-0002-6256-9847 0000-0003-3550-5378 0000-0001-9691-1906
Record's date: 2024-10-19
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/10.1002/jsfa.12305
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of The Science Of Food And Agriculture. 103 (4): 1660-1667
APA: Miguens-Gomez, Alba; Sierra-Cruz, Marta; Segu, Helena; Beltran-Debon, Raul; Rodriguez-Gallego, Esther; Terra, Ximena; Teresa Blay, Maria; Maria Perez- (2023). Administration of Alphitobius diaperinus or Tenebrio molitor before meals transiently increases food intake through enterohormone regulation in female rats. Journal Of The Science Of Food And Agriculture, 103(4), 1660-1667. DOI: 10.1002/jsfa.12305
Article's DOI: 10.1002/jsfa.12305
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV