Author, as appears in the article.: Miguens-Gomez, Alba; Sierra-Cruz, Marta; Segu, Helena; Beltran-Debon, Raul; Rodriguez-Gallego, Esther; Terra, Ximena; Teresa Blay, Maria; Maria Perez-Vendrell, Anna; Pinent, Montserrat; Ardevol, Anna
Department: Bioquímica i Biotecnologia
URV's Author/s: Ardévol Grau, Anna / Beltrán Debón, Raúl Alejandro / Blay Olivé, Maria Teresa / Miguéns Gómez, Alba / Pinent Armengol, Montserrat / Rodríguez Gallego, Esther / Segú Matamoros, Helena / Sierra Cruz, Marta / Terra Barbadora, Ximena
Keywords: Vitro digestion method; Tenebrio; Rats; Meals; Insecta; Insect; Gut; Glucagon-like peptide 1; Ghrelin; Food intake; Female; Enterohormones; Eating; Dietary protein; Coleoptera; Cattle; Animals; yellow mealworm; release; protein; insect; gut; growth-performance; glp-1; ghrelin; food intake; enterohormones; enteroendocrine cells; blood profiles
Abstract: BACKGROUND: It has been previously shown that acutely administered insect Alphitobius diaperinus protein increases food intake in rats and modifies the ex vivo enterohormone secretory profile differently than beef or almond proteins. In this study, we aimed to evaluate whether these effects could be maintained for a longer period and determine the underlying mechanisms. RESULTS: We administered two different insect species to rats for 26 days and measured food intake at different time points. Both insect species increased food intake in the first week, but the effect was later lost. Glucagon-like peptide 1 (GLP-1) and ghrelin were measured in plasma and ex vivo, and no chronic effects on their secretion or desensitization were found. Nevertheless, digested A. diaperinus acutely modified GLP-1 and ghrelin secretion ex vivo. CONCLUSION: Our results suggest that increases in food intake could be explained by a local ghrelin reduction acting in the small intestine. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Thematic Areas: Zootecnia / recursos pesqueiros; Química; Planejamento urbano e regional / demografia; Nutrition and dietetics; Nutrição; Medicina veterinaria; Medicina ii; Medicina i; Materiais; Matemática / probabilidade e estatística; Interdisciplinar; General medicine; Food science & technology; Food science; Farmacia; Engenharias ii; Engenharias i; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Chemistry, applied; Biotecnología; Biotechnology; Biodiversidade; Astronomia / física; Agronomy and crop science; Agriculture, multidisciplinary; Agriculture; Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: alba.miguens@urv.cat; helena.segu@alumni.urv.cat; alba.miguens@urv.cat; alba.miguens@urv.cat; marta.sierra@estudiants.urv.cat; marta.sierra@estudiants.urv.cat; anna.ardevol@urv.cat; ximena.terra@urv.cat; mteresa.blay@urv.cat; esther.rodriguez@urv.cat; montserrat.pinent@urv.cat; raul.beltran@urv.cat
Record's date: 2025-02-18
Paper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/10.1002/jsfa.12305
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Journal Of The Science Of Food And Agriculture. 103 (4): 1660-1667
APA: Miguens-Gomez, Alba; Sierra-Cruz, Marta; Segu, Helena; Beltran-Debon, Raul; Rodriguez-Gallego, Esther; Terra, Ximena; Teresa Blay, Maria; Maria Perez- (2023). Administration of Alphitobius diaperinus or Tenebrio molitor before meals transiently increases food intake through enterohormone regulation in female rats. Journal Of The Science Of Food And Agriculture, 103(4), 1660-1667. DOI: 10.1002/jsfa.12305
Article's DOI: 10.1002/jsfa.12305
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV