Author, as appears in the article.: Reig-Vano, B; Huck-Iriart, C; de la Flor, S; Trojanowska, A; Tylkowski, B; Giamberini, M
Department: Enginyeria Mecànica Enginyeria Química
URV's Author/s: De la Flor Lopez, Silvia / Giamberini, Marta / Reig Vañó, Belén / TROJANOWSKA, ANNA
Keywords: L-guluronic acid Encapsulation Cation-crosslinking Alginate gel physicochemical properties microcapsules metal-ion hydrogels encapsulation divalent-cations delivery degradation coordination cation-crosslinking binding
Abstract: Beads based on a mannuronate(M)-rich alginate (86 % M units) were prepared by adding the polysaccharide solution to a crosslinking bath containing different concentrations (0.5, 2 and 10 wt%) of XCl2 where X = Ca, Cu or Zn. Primarily focus was on Zn, due to its antioxidant, anti-inflammatory and anti-microbial capabilities. The beads were characterized by Field-Emission Scanning Electron Microscopy (FESEM), Fourier-Transform Infra-Red spectroscopy (FT-IR), Thermogravimetric Analysis (TGA), Small-Angle X-ray Scattering (SAXS) and compression tests. The crosslinking agent significantly influenced the properties of the resulting beads. Specifically, Ca-based beads exhibited a smoother surface, while Cu- and Zn-based beads appeared rougher. Interestingly, Zn-based beads displayed a core-shell structure. Young moduli ranged from 3500 and 7000 MPa, with the highest values observed for Zn-beads. SAXS investigation at 0.5 wt% XCl2 suggested increase in the densely packed domains amount in the order: Ca < Cu < Zn. Extended X-ray Absorption Fine Structure (EXAFS) showed that the coordination number was 4.3 ± 0.4 for Cu, and 4.0 ± 0.2 and 1.1 ± 0.1 for Zn in 0.5 wt% XCl2 alginate xerogels, in agreement with reported Density Functional Calculations on Cu2+- and Zn2+-MM complexes. The results from FT-IR, compositional analysis and EXAFS collectively suggested a bridging coordination for these systems.Copyright © 2023. Published by Elsevier B.V.
Thematic Areas: Zootecnia / recursos pesqueiros Structural biology Química Polymer science Planejamento urbano e regional / demografia Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General energy Food science Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Energy (miscellaneous) Economics and econometrics Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, applied Biotecnología Biomaterials Biodiversidade Biochemistry & molecular biology Biochemistry Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: belen.reig@estudiants.urv.cat belen.reig@estudiants.urv.cat marta.giamberini@urv.cat silvia.delaflor@urv.cat
Author identifier: 0000-0001-6402-4499 0000-0001-6402-4499 0000-0001-8278-3552 0000-0002-6851-1371
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0141813023025539
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: International Journal Of Biological Macromolecules. 246 125659-125659
APA: Reig-Vano, B; Huck-Iriart, C; de la Flor, S; Trojanowska, A; Tylkowski, B; Giamberini, M (2023). Structural and mechanical analysis on mannuronate-rich alginate gels and xerogels beads based on Calcium, Copper and Zinc as crosslinkers. International Journal Of Biological Macromolecules, 246(), 125659-125659. DOI: 10.1016/j.ijbiomac.2023.125659
Article's DOI: 10.1016/j.ijbiomac.2023.125659
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV