Articles producció científica> Medicina i Cirurgia

Report on the first two confirmed autochthonous cases of West Nile virus encephalitis in Catalonia, Spain

  • Identification data

    Identifier: imarina:9325788
    Handle: https://hdl.handle.net/20.500.11797/imarina9325788
    Authors:
    García-Cervera, CIftimie, SMMartínez, MJGonzález, AVParra-Pérez, SRevuelta-López-Cordón, LGil-Toral, JVallverdú, RMVMateo, AMLópez-Azcona, AFPujol-Bajador, IBallester-Bastardie, FCastro-Salomó, A
    Abstract:
    West Nile virus (WNV) is a mosquito-borne flavivirus that can cause Central Nervous System infection in humans. Previous autochthonous cases of WNV encephalitis have been described in Spain, but none in Catalonia.We report on the first two autochthonous cases of encephalitis in humans caused by the West Nile virus (WNV) diagnosed in Catalonia (northeastern region of Spain).An old married couple presented with clinical and biological signs compatible with viral encephalitis. Acute and convalescent serum samples showed IgM and IgG positivity for WNV. In addition, IgM was also detected in cerebrospinal fluid in the male patient. The serological results were later confirmed by microneutralization assays.WNV infection must be considered in patients presenting with meningoencephalitis with viral CSF characteristics when common pathogens are excluded.

  • Others:

    Author, as appears in the article.: García-Cervera, C; Iftimie, SM; Martínez, MJ; González, AV; Parra-Pérez, S; Revuelta-López-Cordón, L; Gil-Toral, J; Vallverdú, RMV; Mateo, AM; López-Azcona, AF; Pujol-Bajador, I; Ballester-Bastardie, F; Castro-Salomó, A
    Department: Medicina i Cirurgia
    URV's Author/s: Ballester Bastardie, Frederic / Castro Salomó, Antoni / Iftimie Iftimie, Simona Mihaela / Parra Pérez, Sandra / Pujol Bajador, Isabel
    Keywords: West nile virus Viruses Pcr assay Encephalitis Arboviruses viruses infection encephalitis arboviruses >
    Abstract: West Nile virus (WNV) is a mosquito-borne flavivirus that can cause Central Nervous System infection in humans. Previous autochthonous cases of WNV encephalitis have been described in Spain, but none in Catalonia.We report on the first two autochthonous cases of encephalitis in humans caused by the West Nile virus (WNV) diagnosed in Catalonia (northeastern region of Spain).An old married couple presented with clinical and biological signs compatible with viral encephalitis. Acute and convalescent serum samples showed IgM and IgG positivity for WNV. In addition, IgM was also detected in cerebrospinal fluid in the male patient. The serological results were later confirmed by microneutralization assays.WNV infection must be considered in patients presenting with meningoencephalitis with viral CSF characteristics when common pathogens are excluded.
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: simonamihaela.iftime@urv.cat sandra.parra@urv.cat antoni.castro@urv.cat isabel.pujol@urv.cat frederic.ballester@estudiants.urv.cat
    Author identifier: 0000-0003-0714-8414 0000-0001-9363-6574 0000-0001-5441-6333
    Record's date: 2024-08-03
    Papper version: info:eu-repo/semantics/submittedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Infect Dis (Lond). 55 (11): 1-5
    APA: García-Cervera, C; Iftimie, SM; Martínez, MJ; González, AV; Parra-Pérez, S; Revuelta-López-Cordón, L; Gil-Toral, J; Vallverdú, RMV; Mateo, AM; López-A (2023). Report on the first two confirmed autochthonous cases of West Nile virus encephalitis in Catalonia, Spain. Infect Dis (Lond), 55(11), 1-5. DOI: 10.1080/23744235.2023.2236703
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications

  • Keywords:

    West nile virus
    Viruses
    Pcr assay
    Encephalitis
    Arboviruses
    viruses
    infection
    encephalitis
    arboviruses
    >

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