Author, as appears in the article.: Clivillé-Cabré P; Lacorte S; Borrull F; Fontanals N; Marcé RM
Department: Química Analítica i Química Orgànica
URV's Author/s: Borrull Ballarín, Francesc / Clivillé Cabré, Pol / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria
Keywords: Therapeutic and illicit drugs River water Mixed-mode strong cation-exchange sorbent Liquid chromatography-tandem mass spectrometry Ceramic passive samplers
Abstract: Although most of the analytical methods developed for the monitoring of contaminants in environmental waters are based on discrete grab sampling, an alternative of increasing interest is the use of passive sampling. Methods based on passive sampling provide the sampling and pre-concentration of the analytes in-situ, which makes the sample treatment less time consuming and costly than using discrete grab sampling. In this study, ceramic passive samplers (CPSs) using mixed-mode strong cation-exchange sorbent (Oasis MCX) as retention phase were evaluated for the determination of a group of 21 therapeutic and illicit drugs and some of their metabolites in river water samples that were determined by liquid chromatography-tandem mass spectrometry. After assessing the stability of the analytes, the CPSs were calibrated for 9 days with bottled water and river water, obtaining, for the 19 stable compounds, sample rates (Rs) ranging between 0.180 and 1.767 mL/day and diffusion coefficients (De) between 2.02E-8 and 2.81E-7 cm2/s. Once calibrated, CPSs were deployed for the determination of contaminants in the Ebre River, with good reproducibility, and some of the analytes were determined, including amongst others, gabapentin at 76 ng/L, caffeine at 203 ng/L or diclofenac amine at 57 ng/L. The passive sampling method herein presented is simple and feasible and allows the time-integrated analysis of pharmaceuticals and drugs at trace levels in river water. This study opens the possibility of using other mixed-mode sorbents or other types of sorbents as retaining phase on CPSs for the determination of very polar contaminants in water.
Thematic Areas: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: pol.cliville@urv.cat nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0021967323005733
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Chromatography a. 1708 464348-
APA: Clivillé-Cabré P; Lacorte S; Borrull F; Fontanals N; Marcé RM (2023). Evaluation of ceramic passive samplers using a mixed-mode strong cation-exchange sorbent to monitor polar contaminants in river water. Journal Of Chromatography a, 1708(), 464348-. DOI: 10.1016/j.chroma.2023.464348
Article's DOI: 10.1016/j.chroma.2023.464348
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications