Dietary vitamin D intake and changes in body composition over three years in older adults with metabolic syndrome

Identifier:  imarina:9443125

Handle: https://hdl.handle.net/20.500.11797/imarina9443125

Authors:  Vazquez-Lorente, Hector; Ni, Jiaqi; Babio, Nancy; Garcia-Arellano, Ana; Romaguera, Dora; Martinez, J Alfredo; Estruch, Ramon; Sanchez, Vicente Martin; Vidal, Josep; Fito, Montserrat; Bes-Rastrollo, Maira; Konieczna, Jadwiga; Martinez-Urbistondo, Diego; Casas, Rosa; Garcia-Fernandez, Marcos; Olbeyra, Romina Paula; Chaplin, Alice; Zulet, M Angeles; Salas-Salvado, Jordi

Abstract:
Background: Adequate intake of vitamin D through diet may offer benefits in terms of body composition. Objectives: We aimed to evaluate the longitudinal relationship between dietary vitamin D intake and changes in body composition in older adults over one and three years under the context of a weight loss and lifestyle behavioral intervention. Design: Longitudinal study. Setting: Multicenter. Participants: This longitudinal study included 715 aged participants (mean age 65.3 + 5.0 years, 38% women) with overweight/obesity and metabolic syndrome. Measurements: Multivariable-adjusted mixed-effects linear regression models were fitted to investigate the longitudinal associations between dietary vitamin D intake (exposure) and body composition (outcome) with available data at baseline, one, and three years of follow-up. Data on dietary vitamin D intake was assessed using a validated 143-item food frequency questionnaire. Body composition variables (total body weight (kg), total fat mass (%), total lean mass (%), muscle-to-fat mass ratio, visceral adipose tissue (kg), and android-to-gynoid fat ratio) were measured by dual-energy X-ray absorptiometry. Results: Higher dietary vitamin D intake (for each mu g/day) was associated with higher total lean mass ((3: 0.10 %; 95% CI: 0.02 to 0.18; P: 0.017) and muscle-to-fat mass ratio ((3: 1.00 x 10-2; 95% CI: 0.22 x 10-2 to 1.78 x 10-2; P: 0.011), and lower total body weight ((3:-0.20 kg; 95% CI:-0.34 to-0.05; P: 0.007), total fat mass ((3:-0.11 %; 95% CI:-0.19 to-0.02; P: 0.015), and visceral adipose tissue ((3:-1.74 x 10-2 kg; 95% CI:-3.47 x 10-2 to-0.01 x 10-2; P: 0.048) at one year of follow-up in the group following the intervention in the multivariableadjusted model.