Author, as appears in the article.: Martínez-González MA; Planes FJ; Ruiz-Canela M; Toledo E; Estruch R; Salas-Salvadó J; Valdés-Más R; Mena P; Castañer O; Fitó M; Clish C; Landberg R; Wittenbecher C; Liang L; Guasch-Ferré M; Lamuela-Raventós RM; Wang DD; Forouhi N; Razquin C; Hu FB
Department: Bioquímica i Biotecnologia
URV's Author/s: Salas Salvadó, Jorge
Keywords: Type 2 diabetes Precision nutrition Nutritional epidemiology Metabolomics Mediterranean diet Ischemic heart disease Cardiovascular disease
Abstract: A growing body of research on nutrition omics has led to recent advances in cardiovascular disease epidemiology and prevention. Within the PREDIMED trial, significant associations between diet-related metabolites and cardiovascular disease were identified, which were subsequently replicated in independent cohorts. Some notable metabolites identified include plasma levels of ceramides, acyl-carnitines, branched-chain amino acids, tryptophan, urea cycle pathways, and the lipidome. These metabolites and their related pathways have been associated with incidence of both cardiovascular disease and type 2 diabetes. Future directions in precision nutrition research include: a) developing more robust multimetabolomic scores to predict long-term risk of cardiovascular disease and mortality; b) incorporating more diverse populations and a broader range of dietary patterns; and c) conducting more translational research to bridge the gap between precision nutrition studies and clinical applications.
Thematic Areas: Revistas de ciencias de la salud Medicine (miscellaneous) Medicine (all) Medicina ii Medicina i Interdisciplinar General medicine Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jordi.salas@urv.cat
Author identifier: 0000-0003-2700-7459
Record's date: 2025-03-03
Paper version: info:eu-repo/semantics/publishedVersion
Paper original source: Revista Espanola De Cardiologia. 78 (3): 263-271
APA: Martínez-González MA; Planes FJ; Ruiz-Canela M; Toledo E; Estruch R; Salas-Salvadó J; Valdés-Más R; Mena P; Castañer O; Fitó M; Clish C; Landberg R; W (2025). Recent advances in precision nutrition and cardiometabolic diseases. Revista Espanola De Cardiologia, 78(3), 263-271. DOI: 10.1016/j.recesp.2024.09.005
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2025
Publication Type: Journal Publications
Repositori URV