Tailored-Designed Ligands for Enantioselective Gold(I)-Catalyzed Activation of Alkynes

Identifier:  imarina:9464939

Handle: https://hdl.handle.net/20.500.11797/imarina9464939

Authors:  Mora, P; Escofet, I; Echavarren, A

Abstract:
In this article, we describe the work performed at our laboratories over the years on the design and applications of novel chiral ligands for the enantioselective gold(I)-catalyzed activation of alkynes, with a focus on the cycloisomerization and cycloaddition reactions of 1,6-enynes. The rationale behind the development of each ligand and the mode of enantioinduction are discussed.