Articles producció científicaQuímica Analítica i Química Orgànica

A SERS-active plasmonic nanosensor-chemometrics platform reveals a biphasic zinc switch that controls breast-cancer metastasis

  • Identification data

    Identifier:  imarina:9465586
    Handle: https://hdl.handle.net/20.500.11797/imarina9465586
    Authors:  Zhou, T; Rodríguez-Barrios, S; Ruisánchez, I; Rivera-Gil, P
    Abstract:
    Labile Zn2+ is emerging as a quantitative driver, not just a biomarker, of metastasis, yet rapid, second-resolved intracellular measurement remains elusive. Here we engineer terpyridine-functionalised, hollow Au@SiO2 nanocapsules (NCs@TPY) and couple their SERS signal to cell-specific partial-least-squares (PLS) chemometrics, yielding an 8-log dynamic range (10(-12) - 10(-4) M), a low-nanomolar detection limit and

  • Others:

    Link to the original source: https://www.sciencedirect.com/science/article/pii/S0956566325007730?via%3Dihub
    APA: Zhou, T; Rodríguez-Barrios, S; Ruisánchez, I; Rivera-Gil, P (2025). A SERS-active plasmonic nanosensor-chemometrics platform reveals a biphasic zinc switch that controls breast-cancer metastasis. Biosensors & Bioelectronics, 289(), 117897-. DOI: 10.1016/j.bios.2025.117897
    Paper original source: Biosensors & Bioelectronics. 289 117897-
    Article's DOI: 10.1016/j.bios.2025.117897
    Journal publication year: 2025-12-01
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/publishedVersion
    Record's date: 2026-02-13
    URV's Author/s: Ruisánchez Capelastegui, María Iciar
    Department: Química Analítica i Química Orgànica
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    Author, as appears in the article.: Zhou, T; Rodríguez-Barrios, S; Ruisánchez, I; Rivera-Gil, P
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Thematic Areas: Astronomia / física, Biodiversidade, Biomedical engineering, Biophysics, Biotechnology, Biotechnology & applied microbiology, Biotecnología, Chemistry, analytical, Ciências agrárias i, Ciências ambientais, Ciências biológicas i, Ciências biológicas ii, Ciências biológicas iii, Economia, Electrochemistry, Engenharias ii, Engenharias iii, Engenharias iv, Farmacia, Interdisciplinar, Materiais, Medicina i, Medicina ii, Medicine (miscellaneous), Nanoscience & nanotechnology, Nanoscience and nanotechnology, Química
    Author's mail: itziar.ruisanchez@urv.cat

  • Keywords:

    Breast neoplasms-metastasis
    Cell
    Gold-silica nanocapsules
    Intracellular ion sensing
    Labile zinc
    Multivariate calibration (partial least-squares chemometrics)
    Ph
    Plasmonic nanosensor
    Raman spectroscopy-sers
    Transporter zip10
    Biomedical Engineering
    Biophysics
    Biotechnology
    Biotechnology & Applied Microbiology
    Chemistry
    Analytical
    Electrochemistry
    Medicine (Miscellaneous)
    Nanoscience & Nanotechnology
    Nanoscience and Nanotechnology
    Astronomia / física
    Biodiversidade
    Biotecnología
    Ciências agrárias i
    Ciências ambientais
    Ciências biológicas i
    Ciências biológicas ii
    Ciências biológicas iii
    Economia
    Engenharias ii
    Engenharias iii
    Engenharias iv
    Farmacia
    Interdisciplinar
    Materiais
    Medicina i
    Medicina ii
    Química

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