Articles producció científica> Medicina i Cirurgia

SEOM clinical guidelines for the treatment of follicular non-Hodgkin’s lymphoma

  • Datos identificativos

    Identificador: imarina:2309056
    Autores:
    Provencio Pulla, MarianoAlfaro Lizaso, JCruz Merino, L de laGumà Padró, JosepQuero Blanco, CristinaGómez Codina, JoséLlanos Muñoz, MartaMartínez Banaclocha, NatividadRodríguez Abreu, DelvysRueda Domínguez, Antonio
    Resumen:
    Follicular non-Hodgkin’s lymphoma (FL) is a nodal B lymphoid malignancy that originates from the germinal center of a lymph node. FL is the second most frequent lymphoma subtype. The course of the disease is usually characterised by a typically indolent clinical course, with a median survival rate of 8–10 years, although most patients relapse after treatment. Diagnosis should always be based on a surgical specimen like an excisional node lymph biopsy. The first-line treatment of FL will depend of extension disease, tumour burden, patient symptoms, performance status and also patient decision. The addition of rituximab to conventional chemotherapy has improved ORR, PFS and OS. As first line in patients that need treatment, a combination of chemotherapy with rituximab induction followed by 2 years of rituximab maintenance is the best option. High-dose chemotherapy with autologous stem-cell transplantation in first line has not shown improvement and is not recommended as first-line therapy. Before any treatment decision in relapsed patients, a repeat biopsy is mandatory to rule out a transformation into large cell aggressive lymphoma. Standard treatment is controversial, depends on the efficacy of prior treatment, duration of the time-to-relapse, patient’s age and histological findings at relapse.
  • Otros:

    Autor según el artículo: Provencio Pulla, Mariano; Alfaro Lizaso, J; Cruz Merino, L de la; Gumà Padró, Josep; Quero Blanco, Cristina; Gómez Codina, José; Llanos Muñoz, Marta; Martínez Banaclocha, Natividad; Rodríguez Abreu, Delvys; Rueda Domínguez, Antonio
    Departamento: Medicina i Cirurgia
    Autor/es de la URV: Gumà Padró, José
    Palabras clave: Hashtag Etiqueta «#» @uroweb @residentesaeu @infoAeu
    Resumen: Follicular non-Hodgkin’s lymphoma (FL) is a nodal B lymphoid malignancy that originates from the germinal center of a lymph node. FL is the second most frequent lymphoma subtype. The course of the disease is usually characterised by a typically indolent clinical course, with a median survival rate of 8–10 years, although most patients relapse after treatment. Diagnosis should always be based on a surgical specimen like an excisional node lymph biopsy. The first-line treatment of FL will depend of extension disease, tumour burden, patient symptoms, performance status and also patient decision. The addition of rituximab to conventional chemotherapy has improved ORR, PFS and OS. As first line in patients that need treatment, a combination of chemotherapy with rituximab induction followed by 2 years of rituximab maintenance is the best option. High-dose chemotherapy with autologous stem-cell transplantation in first line has not shown improvement and is not recommended as first-line therapy. Before any treatment decision in relapsed patients, a repeat biopsy is mandatory to rule out a transformation into large cell aggressive lymphoma. Standard treatment is controversial, depends on the efficacy of prior treatment, duration of the time-to-relapse, patient’s age and histological findings at relapse.
    Áreas temáticas: Saúde coletiva Oncology Odontología Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Farmacia Engenharias ii Ciências biológicas ii Ciências biológicas i Cancer research Biotecnología
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1699048X
    Direcció de correo del autor: jose.guma@urv.cat
    Identificador del autor: 0000-0001-7541-9832
    Fecha de alta del registro: 2024-09-07
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689757/
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Clinical & Translational Oncology. 17 (12): 1014,1019-1019
    Referencia de l'ítem segons les normes APA: Provencio Pulla, Mariano; Alfaro Lizaso, J; Cruz Merino, L de la; Gumà Padró, Josep; Quero Blanco, Cristina; Gómez Codina, José; Llanos Muñoz, Marta; (2015). SEOM clinical guidelines for the treatment of follicular non-Hodgkin’s lymphoma. Clinical & Translational Oncology, 17(12), 1014,1019-1019
    DOI del artículo: 10.1007/s12094-015-1437-1
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2015
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Cancer Research,Medicine (Miscellaneous),Oncology
    Saúde coletiva
    Oncology
    Odontología
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina ii
    Medicina i
    Farmacia
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Cancer research
    Biotecnología
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