Autor según el artículo: Martin-Loeches I, Díaz E, Vidaur L, Torres A, Laborda C, Granada R, Bonastre J, Martín M, Insausti J, Arenzana A, Guerrero JE, Navarrete I, Bermejo-Martin J, Suarez D, Rodriguez A, H1N1 SEMICYUC/REIPI/CIBERES Working group
Departamento: Medicina i Cirurgia
Autor/es de la URV: Cabre Vila, Juan Jose / Rodríguez Oviedo, Alejandro Hugo
Palabras clave: Good health and well-being
Resumen: There is a vast amount of information published regarding the impact of 2009 pandemic Influenza A (pH1N1) virus infection. However, a comparison of risk factors and outcome during the 2010-2011 post-pandemic period has not been described.A prospective, observational, multi-center study was carried out to evaluate the clinical characteristics and demographics of patients with positive RT-PCR for H1N1 admitted to 148 Spanish intensive care units (ICUs). Data were obtained from the 2009 pandemic and compared to the 2010-2011 post-pandemic period.Nine hundred and ninety-seven patients with confirmed An/H1N1 infection were included. Six hundred and forty-eight patients affected by 2009 (pH1N1) virus infection and 349 patients affected by the post-pandemic Influenza (H1N1)v infection period were analyzed. Patients during the post-pandemic period were older, had more chronic comorbid conditions and presented with higher severity scores (Acute Physiology And Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA)) on ICU admission. Patients from the post-pandemic Influenza (H1N1)v infection period received empiric antiviral treatment less frequently and with delayed administration. Mortality was significantly higher in the post-pandemic period. Multivariate analysis confirmed that haematological disease, invasive mechanical ventilation and continuous renal replacement therapy were factors independently associated with worse outcome in the two periods. HIV was the only new variable independently associated with higher ICU mortality during the post-pandemic Influenza (H1N1)v infection period.Patients from the post-pandemic Influenza (H1N1)v infection period had an unexpectedly higher mortality rate and showed a trend towards affecting a more vulnerable population, in keeping with more typical seasonal viral infection.
Áreas temáticas: Saúde coletiva Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Engenharias iv Enfermagem Educação física Critical care medicine Critical care and intensive care medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1466609X
Direcció de correo del autor: juanjose.cabre@urv.cat alejandrohugo.rodriguez@urv.cat
Identificador del autor: 0000-0003-1082-6861 0000-0001-8828-5984
Fecha de alta del registro: 2024-11-16
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://ccforum.biomedcentral.com/articles/10.1186/cc10573
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Critical Care. 15 (6): R286-R286
Referencia de l'ítem segons les normes APA: Martin-Loeches I, Díaz E, Vidaur L, Torres A, Laborda C, Granada R, Bonastre J, Martín M, Insausti J, Arenzana A, Guerrero JE, Navarrete I, Bermejo-Ma (2011). Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients. Critical Care, 15(6), R286-R286. DOI: 10.1186/cc10573
DOI del artículo: 10.1186/cc10573
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2011
Tipo de publicación: Journal Publications
Repositori URV