Autor según el artículo: Morina, David; Fernandez-Castillejo, Sara; Valls, Rosa-Maria; Pedret, Anna; Taltavull, Nuria; Romeu, Marta; Giralt, Montse; Montero, Manuel; Bernal, Gloria; Faba, Jenny; Perez-Merino, Laura; Gonzalez, Roser; Casajuana, Maria-Carmen; Rodriguez, Aurea; Arola, Luis; Puiggros, Francesc; Moeller, Ingrid; Chetrit, Carles; Martinez-Puig, Daniel; Sola, Rosa;
Departamento: Ciències Mèdiques Bàsiques Medicina i Cirurgia
Autor/es de la URV: FERNÁNDEZ CASTILLEJO, SARA / Giralt Batista, Montserrat / Pedret Figuerola, Anna / Romeu Ferran, Marta / Solà Alberich, Rosa Maria / Taltavull Anglada, Núria / Valls Zamora, Rosa Maria
Palabras clave: Proliferation Osteoarthritis Myogenesis Hyaluronic-acid Efficacy Double-blind Differentiation Cohort Cells
Resumen: u Purpose: To determine the effects of the intake of low-fat yoghurt supplemented with rooster comb extract (RCE) on muscle strength. Methods and results: 148 subjects, with mild knee pain, participated in a randomized, placebo-controlled, double-blind, and parallel study. Muscle strength, knee effusion, and pain perception were measured. C2C12 myoblasts were used to elucidate the mechanisms of action involved. RCE improved total work and mean power in men, and also peak torque in extension by 10%. RCE reduced synovial effusion by 11.8% and pain perception by 24.6%. Both RCE and HA increased myoblast proliferation by 29%, while RCE reduced myoblast differentiation by 36.2%, suggesting a beneficial role of RCE in muscle regeneration. Conclusions: Low-fat yoghurt supplemented with RCE improved muscle strength. This effect is partially explained by muscle regeneration enhancement, reduced synovial effusion, and reduced pain perception, which could exert a beneficial clinical impact on men affected by mild knee pain.
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biochemistry & molecular biology
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 29938270
Direcció de correo del autor: anna.pedret@urv.cat nuria.taltavull@urv.cat montse.giralt@urv.cat rosamaria.valls@urv.cat marta.romeu@urv.cat rosa.sola@urv.cat
Identificador del autor: 0000-0002-5327-932X 0000-0002-3340-2650 0000-0002-7073-577X 0000-0002-3351-0942 0000-0002-2131-1858 0000-0002-8359-235X
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://pubs.rsc.org/en/content/articlelanding/2018/fo/c8fo00286j
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Food & Function. 9 (6): 3244-3253
Referencia de l'ítem segons les normes APA: Morina, David; Fernandez-Castillejo, Sara; Valls, Rosa-Maria; Pedret, Anna; Taltavull, Nuria; Romeu, Marta; Giralt, Montse; Montero, Manuel; Bernal, G (2018). Effectiveness of a low-fat yoghurt supplemented with rooster comb extract on muscle strength in adults with mild knee pain and mechanisms of action on muscle regeneration. Food & Function, 9(6), 3244-3253. DOI: 10.1039/c8fo00286j
DOI del artículo: 10.1039/c8fo00286j
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2018
Tipo de publicación: Journal Publications
Repositori URV