Articles producció científica> Medicina i Cirurgia

Cause-specific mortality after a breast cancer diagnosis: a cohort study of 10,195 women in Girona and Tarragona.

  • Datos identificativos

    Identificador: imarina:4141163
    Autores:
    Ameijide A, Clèries R, Carulla M, Buxó M, Marcos-Gragera R, Martínez JM, Vilardell ML, Vilardell M, Espinàs JA, Borràs JM, Izquierdo Á, Galceran J
    Resumen:
    Evidence suggests an excess of long-term mortality due to cardiovascular diseases, second tumours and other causes in patients diagnosed with invasive breast cancer (BC). Our aim was to assess this risk of death in a cohort of patients diagnosed with BC in Girona and Tarragona, northeastern Spain.Using data from the cancer registries in these areas, a population-based cohort study was carried out including all the women diagnosed with BC during 1985-2004 and followed up until December 31st 2014 (N = 10,195). The standardised mortality ratios (SMRs) were calculated for causes other than BC in the cohort at 10 years (periods 1985-1994/1995-2004) and 20 years (period 1985-1994). The impact of competing causes of death in the long-term survival was evaluated through competing risk analysis.The SMRs at 10 and 20 years for all-cause mortality, except BC, were 1.21 and 1.22. The main causes of mortality showing statistically significant SMR at 10 years were other tumours (colon, lung, corpus uteri, ovary, and haematological), diabetes mellitus, diseases of the nervous system, cardiovascular diseases (after BC, the second competing cause of death among patients diagnosed > 69 years) and diseases of the kidney. Globally, the 10-year SMR was higher in the first period. After 20 years of follow-up (1985-1994 cohort), there were 48.5 excess deaths per 10,000 patient-years for causes other than BC.Women who did not die from BC at 10 or 20 years after the BC diagnosis had 20% higher risk of dying from other causes than women without BC. This excess risk must be clinically considered during 20 years after the BC diagnosis.
  • Otros:

    Autor según el artículo: Ameijide A, Clèries R, Carulla M, Buxó M, Marcos-Gragera R, Martínez JM, Vilardell ML, Vilardell M, Espinàs JA, Borràs JM, Izquierdo Á, Galceran J
    Departamento: Medicina i Cirurgia
    Autor/es de la URV: Espinas Pinol, Josep Alfons / Galceran Padrós, Jaume Josep Maria
    Palabras clave: Young adult Survival rate Spain Side effects Second tumour Risk factors Registries Prognosis Neoplasms, second primary Middle aged Incidence Humans Follow-up studies Female Excess mortality Cohort studies Cause-specific mortality Cause of death Breast neoplasms Breast cancer Aged, 80 and over Aged Adult Adolescent
    Resumen: Evidence suggests an excess of long-term mortality due to cardiovascular diseases, second tumours and other causes in patients diagnosed with invasive breast cancer (BC). Our aim was to assess this risk of death in a cohort of patients diagnosed with BC in Girona and Tarragona, northeastern Spain.Using data from the cancer registries in these areas, a population-based cohort study was carried out including all the women diagnosed with BC during 1985-2004 and followed up until December 31st 2014 (N = 10,195). The standardised mortality ratios (SMRs) were calculated for causes other than BC in the cohort at 10 years (periods 1985-1994/1995-2004) and 20 years (period 1985-1994). The impact of competing causes of death in the long-term survival was evaluated through competing risk analysis.The SMRs at 10 and 20 years for all-cause mortality, except BC, were 1.21 and 1.22. The main causes of mortality showing statistically significant SMR at 10 years were other tumours (colon, lung, corpus uteri, ovary, and haematological), diabetes mellitus, diseases of the nervous system, cardiovascular diseases (after BC, the second competing cause of death among patients diagnosed > 69 years) and diseases of the kidney. Globally, the 10-year SMR was higher in the first period. After 20 years of follow-up (1985-1994 cohort), there were 48.5 excess deaths per 10,000 patient-years for causes other than BC.Women who did not die from BC at 10 or 20 years after the BC diagnosis had 20% higher risk of dying from other causes than women without BC. This excess risk must be clinically considered during 20 years after the BC diagnosis.
    Áreas temáticas: Saúde coletiva Oncology Odontología Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Farmacia Engenharias ii Ciências biológicas ii Ciências biológicas i Cancer research Biotecnología
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1699048X
    Direcció de correo del autor: jaumejosepmaria.galceran@urv.cat
    Fecha de alta del registro: 2024-09-28
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://link.springer.com/article/10.1007/s12094-018-02015-5
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Clinical & Translational Oncology. 21 (8): 1014-1025
    Referencia de l'ítem segons les normes APA: Ameijide A, Clèries R, Carulla M, Buxó M, Marcos-Gragera R, Martínez JM, Vilardell ML, Vilardell M, Espinàs JA, Borràs JM, Izquierdo Á, Galceran J (2019). Cause-specific mortality after a breast cancer diagnosis: a cohort study of 10,195 women in Girona and Tarragona.. Clinical & Translational Oncology, 21(8), 1014-1025. DOI: 10.1007/s12094-018-02015-5
    DOI del artículo: 10.1007/s12094-018-02015-5
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2019
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Cancer Research,Medicine (Miscellaneous),Oncology
    Young adult
    Survival rate
    Spain
    Side effects
    Second tumour
    Risk factors
    Registries
    Prognosis
    Neoplasms, second primary
    Middle aged
    Incidence
    Humans
    Follow-up studies
    Female
    Excess mortality
    Cohort studies
    Cause-specific mortality
    Cause of death
    Breast neoplasms
    Breast cancer
    Aged, 80 and over
    Aged
    Adult
    Adolescent
    Saúde coletiva
    Oncology
    Odontología
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina ii
    Medicina i
    Farmacia
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Cancer research
    Biotecnología
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