Autor según el artículo: Bazal P; Gea A; Navarro AM; Salas-Salvadó J; Corella D; Alonso-Gómez A; Fitó M; Muñoz-Bravo C; Estruch R; Fiol M; Lapetra J; Serra-Majem L; Ros E; Rekondo J; Muñoz MA; Basora J; Sorlí JV; Toledo E; Martínez-González MA; Ruiz-Canela M
Departamento: Bioquímica i Biotecnologia Medicina i Cirurgia
Autor/es de la URV: Basora Gallisa, Josep / Salas Salvadó, Jorge
Palabras clave: Validation Profile Metaanalysis Mediterranean diet Danish diet Coffee Cancer Caffeine Atrial fibrillation mediterranean diet caffeine atrial fibrillation
Resumen: © The European Society of Cardiology 2020. Aims: The association between caffeinated coffee consumption and atrial fibrillation remains unclear. Recent studies suggest an inverse association only between a moderate caffeinated coffee consumption and atrial fibrillation, but others have reported no association. The aim of our study was to prospectively assess the association between caffeinated coffee consumption and atrial fibrillation in two Spanish cohorts, one of adults from a general population and another of elderly participants at high cardiovascular risk. Methods and results: We included 18,983 and 6479 participants from the ‘Seguimiento Universidad de Navarra’ (SUN) and ‘Prevención con Dieta Mediterránea’ (PREDIMED) cohorts, respectively. Participants were classified according to their caffeinated coffee consumption in three groups: ≤3 cups/month, 1–7 cups/week, and >1 cup/day. We identified 97 atrial fibrillation cases after a median follow-up of 10.3 years (interquartile range 6.5–13.5), in the SUN cohort and 250 cases after 4.4 years median follow-up (interquartile range 2.8–5.8) in the PREDIMED study. No significant associations were observed in the SUN cohort although a J-shaped association was suggested. A significant inverse association between the intermediate category of caffeinated coffee consumption (1–7 cups/week) and atrial fibrillation was observed in PREDIMED participants with a multivariable-adjusted hazard ratio = 0.53 (95% confidence interval 0.36–0.79) when compared with participants who did not consume caffeinated coffee or did it only occasionally. No association was found for higher levels of caffeinated coffee consumption (>1 cup per day), hazard ratio = 0.79 (95% confidence interval 0.49–1.28). In the meta-analysis of both PREDIMED and SUN studies, the hazard ratio for intermediate consumption of caffeinated coffee was 0.60 (95% confidence interval 0.44–0.82) without evidence of heterogeneity. Similar findings were found for the association between caffeine intake and atrial fibrillation risk. Conclusion: Intermediate levels of caffeinated coffee consumption (1–7 cups/week) were associated with a reduction in atrial fibrillation risk in two prospective Mediterranean cohorts.
Áreas temáticas: Saúde coletiva Nutrição Medicine (all) Medicina ii Medicina i General medicine Epidemiology Engenharias iv Educação física Ciências biológicas ii Ciências biológicas i Ciência de alimentos Cardiology and cardiovascular medicine Cardiac & cardiovascular systems Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20474873
Direcció de correo del autor: josep.basora@urv.cat josep.basora@urv.cat jordi.salas@urv.cat
Identificador del autor: 0000-0003-2700-7459
Fecha de alta del registro: 2024-07-27
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://journals.sagepub.com/doi/abs/10.1177/2047487320909065
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: European Journal Of Preventive Cardiology. 28 (6): 648-657
Referencia de l'ítem segons les normes APA: Bazal P; Gea A; Navarro AM; Salas-Salvadó J; Corella D; Alonso-Gómez A; Fitó M; Muñoz-Bravo C; Estruch R; Fiol M; Lapetra J; Serra-Majem L; Ros E; Rek (2021). Caffeinated coffee consumption and risk of atrial fibrillation in two Spanish cohorts. European Journal Of Preventive Cardiology, 28(6), 648-657. DOI: 10.1177/2047487320909065
DOI del artículo: 10.1177/2047487320909065
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Tipo de publicación: Journal Publications
Repositori URV