Autor según el artículo: Blanco-Formoso M; Alvarez-Puebla RA
Departamento: Química Física i Inorgànica
Autor/es de la URV: Alvarez Puebla, Ramon Angel
Palabras clave: Ultrasensitive detection Tirf Telomerase activity Spr Sers Quantification Plasmonic nanoparticles Mirna Microscopy Metaanalysis Liquid biopsy Label-free Gold nanoparticles Enhanced raman-scattering Dna Dls Diagnosis Circulating tumor cells Cancer Biomarkers tirf spr sers mirna liquid biopsy dls diagnosis circulating tumor cells cancer
Resumen: Cancer heterogeneity increasingly requires ultrasensitive techniques that allow early diagnosis for personalized treatment. In addition, they should preferably be non-invasive tools that do not damage surrounding tissues or contribute to body toxicity. In this context, liquid biopsy of biological samples such as urine, blood, or saliva represents an ideal approximation of what is happening in real time in the affected tissues. Plasmonic nanoparticles are emerging as an alternative or complement to current diagnostic techniques, being able to detect and quantify novel biomarkers such as specific peptides and proteins, microRNA, circulating tumor DNA and cells, and exosomes. Here, we review the latest ideas focusing on the use of plasmonic nanoparticles in coded and label-free surface-enhanced Raman scattering (SERS) spectroscopy. Moreover, surface plasmon resonance (SPR) spectroscopy, colorimetric assays, dynamic light scattering (DLS) spectroscopy, mass spectrometry or total internal reflection fluorescence (TIRF) microscopy among others are briefly examined in order to highlight the potential and versatility of plasmonics.
Áreas temáticas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 14220067
Direcció de correo del autor: ramon.alvarez@urv.cat
Identificador del autor: 0000-0003-4770-5756
Fecha de alta del registro: 2023-02-19
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/1422-0067/21/6/2253
Referencia al articulo segun fuente origial: International Journal Of Molecular Sciences. 21 (6):
Referencia de l'ítem segons les normes APA: Blanco-Formoso M; Alvarez-Puebla RA (2020). Cancer Diagnosis through SERS and Other Related Techniques. International Journal Of Molecular Sciences, 21(6), -. DOI: 10.3390/ijms21062253
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.3390/ijms21062253
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV