Autor según el artículo: Blanco-Formoso M; Alvarez-Puebla RA

Departamento: Química Física i Inorgànica

Autor/es de la URV: Alvarez Puebla, Ramon Angel

Palabras clave: Ultrasensitive detection Tirf Telomerase activity Spr Sers Quantification Plasmonic nanoparticles Mirna Microscopy Metaanalysis Liquid biopsy Label-free Gold nanoparticles Enhanced raman-scattering Dna Dls Diagnosis Circulating tumor cells Cancer Biomarkers tirf spr sers mirna liquid biopsy dls diagnosis circulating tumor cells cancer

Resumen: Cancer heterogeneity increasingly requires ultrasensitive techniques that allow early diagnosis for personalized treatment. In addition, they should preferably be non-invasive tools that do not damage surrounding tissues or contribute to body toxicity. In this context, liquid biopsy of biological samples such as urine, blood, or saliva represents an ideal approximation of what is happening in real time in the affected tissues. Plasmonic nanoparticles are emerging as an alternative or complement to current diagnostic techniques, being able to detect and quantify novel biomarkers such as specific peptides and proteins, microRNA, circulating tumor DNA and cells, and exosomes. Here, we review the latest ideas focusing on the use of plasmonic nanoparticles in coded and label-free surface-enhanced Raman scattering (SERS) spectroscopy. Moreover, surface plasmon resonance (SPR) spectroscopy, colorimetric assays, dynamic light scattering (DLS) spectroscopy, mass spectrometry or total internal reflection fluorescence (TIRF) microscopy among others are briefly examined in order to highlight the potential and versatility of plasmonics.

Áreas temáticas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 14220067

Direcció de correo del autor: ramon.alvarez@urv.cat

Identificador del autor: 0000-0003-4770-5756

Fecha de alta del registro: 2023-02-19

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.mdpi.com/1422-0067/21/6/2253

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: International Journal Of Molecular Sciences. 21 (6):

Referencia de l'ítem segons les normes APA: Blanco-Formoso M; Alvarez-Puebla RA (2020). Cancer Diagnosis through SERS and Other Related Techniques. International Journal Of Molecular Sciences, 21(6), -. DOI: 10.3390/ijms21062253

DOI del artículo: 10.3390/ijms21062253

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2020

Tipo de publicación: Journal Publications