Metabolomic charactetization of yeast cells after dehydration stress

Identificador:  imarina:6388188

Handle: https://hdl.handle.net/20.500.11797/imarina6388188

Autores:  López-Martínez, G; Borrull, A; Poblet, M; Rozès, N; Cordero-Otero, R

Resumen:
© 2014, Sociedad Espanola de Microbiologia. All rights reserevd. In this study, we analyzed the metabolite features of the yeasts Saccharomyces cerevisiae, Naumovia castellii, and Saccharomyces mikatae. The three species are closely related genetically but differ in their tolerance of desiccation stress. Specifi cally, we determined whether certain metabolites correlated with cell viability after stress imposition. The metabolomics profi les of these strains were compared before cell desiccation and after cell rehydration. In S. mikatae, the presence of lysine or glutamine during rehydration led to a 20% increase in survival whereas during dehydration the levels of both amino acids in this yeast were drastically reduced.