Autor según el artículo: Louro J; Román M; Posso M; Comerma L; Vidal C; Saladié F; Alcantara R; Sanchez M; Quintana MJ; Del Riego J; Ferrer J; Peñalva L; Bargalló X; Prieto M; Sala M; Castells X

Departamento: Ciències Mèdiques Bàsiques

Autor/es de la URV: SALADIÉ ROIGET, FRANCINA

Palabras clave: Risk factors Early cancer detection Breast neoplasms Benign breast disease

Resumen: © 2020 Introduction: We aimed to assess differences in breast cancer risk across benign breast disease diagnosed at prevalent or incident screens. Materials and methods: We conducted a retrospective cohort study with data from 629,087 women participating in a long-standing population-based breast cancer screening program in Spain. Each benign breast disease was classified as non-proliferative, proliferative without atypia, or proliferative with atypia, and whether it was diagnosed in a prevalent or incident screen. We used partly conditional Cox hazard regression to estimate the adjusted hazard ratios of the risk of breast cancer. Results: Compared with women without benign breast disease, the risk of breast cancer was significantly higher (p-value = 0.005) in women with benign breast disease diagnosed in an incident screen (aHR, 2.67; 95%CI: 2.24–3.19) than in those with benign breast disease diagnosed in a prevalent screen (aHR, 1.87; 95%CI: 1.57–2.24). The highest risk was found in women with a proliferative benign breast disease with atypia (aHR, 4.35; 95%CI: 2.09–9.08, and 3.35; 95%CI: 1.51–7.40 for those diagnosed at incident and prevalent screens, respectively), while the lowest was found in women with non-proliferative benign breast disease (aHR, 2.39; 95%CI: 1.95–2.93, and 1.63; 95%CI: 1.32–2.02 for those diagnosed at incident and prevalent screens, respectively). Conclusion: Our study showed that the risk of breast cancer conferred by a benign breast disease differed according to type of screen (prevalent or incident). To our knowledge, this is the first study to analyse the impact of the screening type on benign breast disease prognosis.

Áreas temáticas: Surgery Sociología Saúde coletiva Oncology Odontología Obstetrics & gynecology Medicine (miscellaneous) Medicina iii Medicina ii Medicina i General medicine Educação física Ciências biológicas ii Ciências biológicas i Cancer research Biotecnología

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: francina.saladie@urv.cat

Fecha de alta del registro: 2022-07-10

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.thebreastonline.com/article/S0960-9776(20)30182-X/fulltext#%20

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Breast. 54 343-348

Referencia de l'ítem segons les normes APA: Louro J; Román M; Posso M; Comerma L; Vidal C; Saladié F; Alcantara R; Sanchez M; Quintana MJ; Del Riego J; Ferrer J; Peñalva L; Bargalló X; Prieto M; (2020). Differences in breast cancer risk after benign breast disease by type of screening diagnosis. Breast, 54(), 343-348. DOI: 10.1016/j.breast.2020.09.005

DOI del artículo: 10.1016/j.breast.2020.09.005

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2020

Tipo de publicación: Journal Publications