Autor según el artículo: Pamies, Oscar; Margalef, Jessica; Canellas, Santiago; James, Jinju; Judge, Eric; Guiry, Patrick J; Moberg, Christina; Backvall, Jan-E; Pfaltz, Andreas; Pericas, Miquel A; Dieguez, Montserrat
Departamento: Química Física i Inorgànica
Autor/es de la URV: Diéguez Fernández, Montserrat / MARGALEF LLEBARIA, JOAQUIM / Pamies Ollé, Oscar / Pericàs Brondo, Miquel Àngel
Palabras clave: Transition-metal Phosphite-oxazoline ligands Linked bis(oxazoline) ligands Kinetic resolution Force-field parameters Chiral diaminophosphine oxide Carbon quaternary stereocenters C-h oxidation Asymmetric 3+2 cycloaddition Alkylation total-synthesis
Resumen: This Review compiles the evolution, mechanistic understanding, and more recent advances in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic substitutions. For each reaction, the catalytic data, as well as examples of their application to the synthesis of more complex molecules, are collected. Sections in which we discuss key mechanistic aspects for high selectivity and a comparison with other metals (with advantages and disadvantages) are also included. For Pd-catalyzed asymmetric allylic substitution, the catalytic data are grouped according to the type of nucleophile employed. Because of the prominent position of the use of stabilized carbon nucleophiles and heteronucleophiles, many chiral ligands have been developed. To better compare the results, they are presented grouped by ligand types. Pd-catalyzed asymmetric decarboxylative reactions are mainly promoted by PHOX or Trost ligands, which justifies organizing this section in chronological order. For asymmetric oxidative allylic substitution the results are grouped according to the type of nucleophile used.
Áreas temáticas: Química Materiais General medicine General chemistry Farmacia Engenharias iii Engenharias ii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: miquelangel.pericas@urv.cat oscar.pamies@urv.cat montserrat.dieguez@urv.cat
Identificador del autor: 0000-0002-2352-8508 0000-0002-8450-0656
Fecha de alta del registro: 2024-11-09
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/acs.chemrev.0c00736
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Chemical Reviews. 121 (8): 4373-4505
Referencia de l'ítem segons les normes APA: Pamies, Oscar; Margalef, Jessica; Canellas, Santiago; James, Jinju; Judge, Eric; Guiry, Patrick J; Moberg, Christina; Backvall, Jan-E; Pfaltz, Andreas (2021). Recent Advances in Enantioselective Pd-Catalyzed Allylic Substitution: From Design to Applications. Chemical Reviews, 121(8), 4373-4505. DOI: 10.1021/acs.chemrev.0c00736
DOI del artículo: 10.1021/acs.chemrev.0c00736
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Tipo de publicación: Journal Publications