Autor según el artículo: Chen C; Shi M; Liao Z; Chen W; Wu Y; Tian X
Departamento: Infermeria
Autor/es de la URV: Tian, Xu
Palabras clave: Task-force Suboptimal bowel preparation Standard peg Split method Solution oss Reduced-volume Polyethylene-glycol Oral sulfate solution Impact Colorectal-cancer Colorectal cancer Colonoscopy Bowel preparation Ascorbic-acid Adenoma
Resumen: Objectives Although oral sulfate solution (OSS) has been revealed to be not only safe and efficacious but also noninferior to polyethylene glycol with ascorbic acid (PEG + ASC), it is unclear whether OSS can ultimately increase the polyp detection rate (PDR) and adenoma detection rate (ADR). We performed this meta-analysis to estimate the effect of OSS on PDR and ADR during colonoscopy. Methods We searched PubMed, EMBASE, and the Cochrane Library to identify relevant randomized controlled trials (RCTs) investigating the comparative effect of OSS versus PEG + ASC on the PDR and ADR during colonoscopy. Cecal intubation time (CIT), cecal intubation rate (CIR), and bowel preparation score were also evaluated. Review Manager (RevMan) version 5.3.0 was used to perform statistical analysis. Results Eight RCTs involving 2059 patients fulfilled the selection criteria. Meta-analysis suggested that OSS significantly increased the PDR (47.34% vs. 40.14%, risk ratio [RR] 1.13, 95% confidence interval [CI] 1.03-1.24, P = 0.01) and ADR (44.60% vs. 38.14%, RR 1.17, 95% CI 1.03-1.33, P = 0.01) during colonoscopy. Subgroup analysis showed that the beneficial effects of OSS on PDR and ADR were consistent among patients with mean age >55 years and with body mass index <25 kg/m(2) receiving outpatient colonoscopy, morning colonoscopy, and the 2-L bowel preparation protocol. Meanwhile, patients receiving OSS had a beneficial bowel preparation score. Conclusion Compared with polyethylene glycol-based regimens, the OSS bowel preparation regimen significantly increased the PDR and ADR in patients undergoing colonoscopy.
Áreas temáticas: Surgery Saúde coletiva Radiology, nuclear medicine and imaging Medicina iii Medicina ii Medicina i Gastroenterology & hepatology Gastroenterology Ciências biológicas ii
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: xu.tian@estudiants.urv.cat
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/10.1111/den.14299
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Digestive Endoscopy.
Referencia de l'ítem segons les normes APA: Chen C; Shi M; Liao Z; Chen W; Wu Y; Tian X (2022). Oral sulfate solution benefits polyp and adenoma detection during colonoscopy: Meta-analysis of randomized controlled trials. Digestive Endoscopy, (), -. DOI: 10.1111/den.14299
DOI del artículo: 10.1111/den.14299
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2022
Tipo de publicación: Journal Publications