Autor según el artículo: Navarro-Masip, E; Manocchio, F; Colom-Pellicer, M; Escoté, X; Iglesias-Carres, L; Calvo, E; Bravo, F; Muguerza, B; Desjardins, Y; Aragonés, G
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Aragonès Bargalló, Gerard / Bravo Vázquez, Francisca Isabel / Calvo Manso, Enrique / Colom Pellicer, Marina / Escote Miro, Xavier / Manocchio, Francesca / Muguerza Marquínez, Maria Begoña / Navarro Masip, Èlia
Palabras clave: Xenohormesis Ucp1 Photoperiod Grapes Gene-expression Biological rhythms xenohormesis ucp1 photoperiod obesity muscle grapes fischer-344 rats extract
Resumen: The beneficial health effects of (poly)phenol-rich foods such as red grapes mainly depend on both the type and concentration of (poly)phenols. Since fruit (poly)phenol content is influenced by growing conditions, the study examines the seasonal effects of red grapes (Vitis vinifera L.), grown under various cultivation conditions, on metabolic markers of adipose tissue in healthy rats.For this purpose, Fischer 344 rats are exposed into three different light-dark cycles and daily supplemented with 100 mg kg-1 of either conventionally or organically grown red grapes for 10 weeks (n = 6). Seasonal consumption of organic grapes (OGs), which are richer in anthocyanins, increases energy expenditure (EE) of animals exposed to long photoperiod and enhances uncoupling protein 1 (UCP1) protein expression in brown adipose tissue of animals under standard photoperiod. Additionally, red grape consumption affects the gene expression profile of white adipose tissue (WAT), upregulating browning markers of subcutaneous WAT in 12 h light (L12) and 18 h light (L18) photoperiods, and downregulating adipogenic and lipolytic markers of visceral WAT in 6 h light (L6) and L12 photoperiods.These results clearly show that bioactive compounds of grapes can modulate the metabolic markers of white and brown adipose tissues in a photoperiod and depot-dependent manner, partly affecting EE when consumed out of season.© 2023 The Authors. Molecular Nutrition & Food Research published by Wiley-VCH GmbH.
Áreas temáticas: Saúde coletiva Química Nutrição Medicina veterinaria Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biotechnology Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: marina.colom@urv.cat enrique.calvo@urv.cat xavier.escote@urv.cat marina.colom@urv.cat marina.colom@urv.cat francesca.manocchio@urv.cat francesca.manocchio@urv.cat francesca.manocchio@urv.cat elia.navarro@estudiants.urv.cat elia.navarro@estudiants.urv.cat franciscaisabel.bravo@urv.cat gerard.aragones@urv.cat begona.muguerza@urv.cat
Identificador del autor: 0000-0003-1172-3995 0000-0002-6468-3088 0000-0001-7384-8588
Fecha de alta del registro: 2024-09-21
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/full/10.1002/mnfr.202300074
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Molecular Nutrition & Food Research. 67 (17): e2300074-e2300074
Referencia de l'ítem segons les normes APA: Navarro-Masip, E; Manocchio, F; Colom-Pellicer, M; Escoté, X; Iglesias-Carres, L; Calvo, E; Bravo, F; Muguerza, B; Desjardins, Y; Aragonés, G (2023). Vitis vinifera L. Bioactive Components Modulate Adipose Tissue Metabolic Markers of Healthy Rats in a Photoperiod-Dependent Manner. Molecular Nutrition & Food Research, 67(17), e2300074-e2300074. DOI: 10.1002/mnfr.202300074
DOI del artículo: 10.1002/mnfr.202300074
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2023
Tipo de publicación: Journal Publications