Autor según el artículo: Ramírez-Maldonado, E; Gordo, SL; Branco, RPM; Pavel, MC; Estalella, L; Llàcer-Millán, E; Guerrero, MA; López-Gordo, E; Memba, R; Jorba, R
Departamento: Medicina i Cirurgia
Autor/es de la URV: Estalella Mercadé, Laia / Jorba Martin, Rosa Maria / Llàcer Millán, Erik / Memba Ikuga, Roberto / Pavel, Mihai-Calin / Ramírez Maldonado, Ruby Elena
Palabras clave: Pancreatic ductal adenocarcinoma Mutations Micrornas Metaanalysis Liquid biopsy Kras Juice Free dna Extracellular vesicles Epithelial-cells Diagnostic-value Circulating tumor-cells Circulating tumor dna Circulating tumor cells Circulating free tumor dna Biomarker
Resumen: Pancreatic ductal adenocarcinoma contributes significantly to global cancer-related deaths, featuring only a 10% survival rate over five years. The quest for novel tumor markers is critical to facilitate early diagnosis and tailor treatment strategies for this disease, which is key to improving patient outcomes. In pancreatic ductal adenocarcinoma, these markers have been demonstrated to play a crucial role in early identification, continuous monitoring, and prediction of its prognosis and have led to better patient outcomes. Nowadays, biopsy specimens serve to ascertain diagnosis and determine tumor type. However, liquid biopsies present distinct advantages over conventional biopsy techniques. They offer a noninvasive, easily administered procedure, delivering insights into the tumor's status and facilitating real-time monitoring. Liquid biopsies encompass a variety of elements, such as circulating tumor cells, circulating tumor DNA, extracellular vesicles, microRNAs, circulating RNA, tumor platelets, and tumor endothelial cells. This review aims to provide an overview of the clinical applications of liquid biopsy as a technique in the management of pancreatic cancer.
Áreas temáticas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: mihai-calin.pavel@urv.cat laia.estalella@urv.cat roberto.memba@urv.cat erik.llacer@urv.cat rubyelena.ramirez@urv.cat rosamaria.jorba@urv.cat
Identificador del autor: 0000-0003-3307-4340
Fecha de alta del registro: 2024-08-03
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/1422-0067/25/3/1640
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: International Journal Of Molecular Sciences. 25 (3):
Referencia de l'ítem segons les normes APA: Ramírez-Maldonado, E; Gordo, SL; Branco, RPM; Pavel, MC; Estalella, L; Llàcer-Millán, E; Guerrero, MA; López-Gordo, E; Memba, R; Jorba, R (2024). Clinical Application of Liquid Biopsy in Pancreatic Cancer: A Narrative Review. International Journal Of Molecular Sciences, 25(3), -. DOI: 10.3390/ijms25031640
DOI del artículo: 10.3390/ijms25031640
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications