Articles producció científica> Medicina i Cirurgia

Clinical Application of Liquid Biopsy in Pancreatic Cancer: A Narrative Review

  • Datos identificativos

    Identificador: imarina:9363668
    Autores:
    Ramírez-Maldonado, EGordo, SLBranco, RPMPavel, MCEstalella, LLlàcer-Millán, EGuerrero, MALópez-Gordo, EMemba, RJorba, R
    Resumen:
    Pancreatic ductal adenocarcinoma contributes significantly to global cancer-related deaths, featuring only a 10% survival rate over five years. The quest for novel tumor markers is critical to facilitate early diagnosis and tailor treatment strategies for this disease, which is key to improving patient outcomes. In pancreatic ductal adenocarcinoma, these markers have been demonstrated to play a crucial role in early identification, continuous monitoring, and prediction of its prognosis and have led to better patient outcomes. Nowadays, biopsy specimens serve to ascertain diagnosis and determine tumor type. However, liquid biopsies present distinct advantages over conventional biopsy techniques. They offer a noninvasive, easily administered procedure, delivering insights into the tumor's status and facilitating real-time monitoring. Liquid biopsies encompass a variety of elements, such as circulating tumor cells, circulating tumor DNA, extracellular vesicles, microRNAs, circulating RNA, tumor platelets, and tumor endothelial cells. This review aims to provide an overview of the clinical applications of liquid biopsy as a technique in the management of pancreatic cancer.
  • Otros:

    Autor según el artículo: Ramírez-Maldonado, E; Gordo, SL; Branco, RPM; Pavel, MC; Estalella, L; Llàcer-Millán, E; Guerrero, MA; López-Gordo, E; Memba, R; Jorba, R
    Departamento: Medicina i Cirurgia
    Autor/es de la URV: Estalella Mercadé, Laia / Jorba Martin, Rosa Maria / Llàcer Millán, Erik / Memba Ikuga, Roberto / Pavel, Mihai-Calin / Ramírez Maldonado, Ruby Elena
    Palabras clave: Pancreatic ductal adenocarcinoma Mutations Micrornas Metaanalysis Liquid biopsy Kras Juice Free dna Extracellular vesicles Epithelial-cells Diagnostic-value Circulating tumor-cells Circulating tumor dna Circulating tumor cells Circulating free tumor dna Biomarker
    Resumen: Pancreatic ductal adenocarcinoma contributes significantly to global cancer-related deaths, featuring only a 10% survival rate over five years. The quest for novel tumor markers is critical to facilitate early diagnosis and tailor treatment strategies for this disease, which is key to improving patient outcomes. In pancreatic ductal adenocarcinoma, these markers have been demonstrated to play a crucial role in early identification, continuous monitoring, and prediction of its prognosis and have led to better patient outcomes. Nowadays, biopsy specimens serve to ascertain diagnosis and determine tumor type. However, liquid biopsies present distinct advantages over conventional biopsy techniques. They offer a noninvasive, easily administered procedure, delivering insights into the tumor's status and facilitating real-time monitoring. Liquid biopsies encompass a variety of elements, such as circulating tumor cells, circulating tumor DNA, extracellular vesicles, microRNAs, circulating RNA, tumor platelets, and tumor endothelial cells. This review aims to provide an overview of the clinical applications of liquid biopsy as a technique in the management of pancreatic cancer.
    Áreas temáticas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: mihai-calin.pavel@urv.cat laia.estalella@urv.cat roberto.memba@urv.cat erik.llacer@urv.cat rubyelena.ramirez@urv.cat rosamaria.jorba@urv.cat
    Identificador del autor: 0000-0003-3307-4340
    Fecha de alta del registro: 2024-08-03
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.mdpi.com/1422-0067/25/3/1640
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: International Journal Of Molecular Sciences. 25 (3):
    Referencia de l'ítem segons les normes APA: Ramírez-Maldonado, E; Gordo, SL; Branco, RPM; Pavel, MC; Estalella, L; Llàcer-Millán, E; Guerrero, MA; López-Gordo, E; Memba, R; Jorba, R (2024). Clinical Application of Liquid Biopsy in Pancreatic Cancer: A Narrative Review. International Journal Of Molecular Sciences, 25(3), -. DOI: 10.3390/ijms25031640
    DOI del artículo: 10.3390/ijms25031640
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2024
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Biochemistry & Molecular Biology,Catalysis,Chemistry, Multidisciplinary,Computer Science Applications,Inorganic Chemistry,Medicine (Miscellaneous),Molecular Biology,Organic Chemistry,Physical and Theoretical Chemistry,Spectroscopy
    Pancreatic ductal adenocarcinoma
    Mutations
    Micrornas
    Metaanalysis
    Liquid biopsy
    Kras
    Juice
    Free dna
    Extracellular vesicles
    Epithelial-cells
    Diagnostic-value
    Circulating tumor-cells
    Circulating tumor dna
    Circulating tumor cells
    Circulating free tumor dna
    Biomarker
    Zootecnia / recursos pesqueiros
    Spectroscopy
    Saúde coletiva
    Química
    Psicología
    Physical and theoretical chemistry
    Organic chemistry
    Odontología
    Nutrição
    Molecular biology
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Inorganic chemistry
    Geociências
    Farmacia
    Engenharias iv
    Engenharias ii
    Engenharias i
    Educação física
    Computer science applications
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Chemistry, multidisciplinary
    Catalysis
    Biotecnología
    Biodiversidade
    Biochemistry & molecular biology
    Astronomia / física
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