Conjunts de dades de producció científicaBioquímica i Biotecnologia

Replication data for Linking intestinal bitter taste receptors and GSPE-induced long-lasting benefits in ageing rats: an integrative analysis

  • Identification data

    Identifier:  PC:4920
    Handle: https://hdl.handle.net/20.500.11797/PC4920
    Authors:  Terra, Ximena; Vilalta, Adrià; Descamps Solà, Maria; Sierra Cruz, Marta; MIGUÉNS GÓMEZ, ALBA; Beltrán-Debón, Raúl; Rodríguez-Gallego, Esther; Pinent, Montserrat; Ardévol, Anna
    Abstract:
    This dataset contains all experimental measurements generated for the study published in Food & Function (2026), which investigates how ageing alters the intestinal expression of bitter taste receptors (Tas2rs) in rats and whether a short intervention with grape-seed proanthocyanidin extract (GSPE) can induce long-lasting physiological reprogramming. The dataset includes raw values covering physiological, biochemical, metabolic, gene expression, microbiota and ex vivo intestinal function variables, obtained from female Wistar rats allocated into three groups: young (2 months), aged (21 months), and aged animals supplemented with GSPE for 10 days and analysed after a 75-day wash-out period. All data required to reproduce the statistical analyses, machine-learning variable selection and partial-correlation network presented in the article are provided, allowing secondary analyses on intestinal ageing, barrier function, inflammation, metabolomics and microbiota composition

  • Others:

    Subject matter: Medicine, Health and Life Sciences
    Access rights: info:eu-repo/semantics/openAccess
    Researcher identifier: 0000-0003-1043-5844; 0000-0002-9909-4128; 0009-0009-7400-8578; 0000-0002-1904-7859; 0000-0003-1567-0018; 0000-0001-9691-1906; 0000-0002-6363-2510; 0000-0003-3550-5378; 0000-0003-0156-7538
    Published by (editorial): Universitat Rovira i Virgili (URV)
    Language: en
    Related publications: Vilalta A., Descamps-Solà M., Sierra-Cruz M., et al. Linking intestinal bitter taste receptors and GSPE-induced long-lasting benefits in ageing rats: an integrative analysis. Food & Function. 2026;17:1336–1349. doi 10.1039/d5fo03241e http://rsc.li/food-function
    Funding program: Agencia Estatal de Investigación; Generalitat de Catalunya
    Abstract: This dataset contains all experimental measurements generated for the study published in Food & Function (2026), which investigates how ageing alters the intestinal expression of bitter taste receptors (Tas2rs) in rats and whether a short intervention with grape-seed proanthocyanidin extract (GSPE) can induce long-lasting physiological reprogramming. The dataset includes raw values covering physiological, biochemical, metabolic, gene expression, microbiota and ex vivo intestinal function variables, obtained from female Wistar rats allocated into three groups: young (2 months), aged (21 months), and aged animals supplemented with GSPE for 10 days and analysed after a 75-day wash-out period. All data required to reproduce the statistical analyses, machine-learning variable selection and partial-correlation network presented in the article are provided, allowing secondary analyses on intestinal ageing, barrier function, inflammation, metabolomics and microbiota composition
    Departament: Bioquímica i Biotecnologia
    DOI: https://doi.org/10.34810/data3051
    Document type: info:eu-repo/semantics/other
    Project code: PID2021-122636OB-I00; 2021 SGR 00201
    Related publication's DOI: 10.1039/D5FO03241E
    Author: Terra, Ximena; Vilalta, Adrià; Descamps Solà, Maria; Sierra Cruz, Marta; MIGUÉNS GÓMEZ, ALBA; Beltrán-Debón, Raúl; Rodríguez-Gallego, Esther; Pinent, Montserrat; Ardévol, Anna
    Keywords: Metabolism; Immflamation; Microbiota
    Dataset publication year: 2026
    Dataset title: Replication data for Linking intestinal bitter taste receptors and GSPE-induced long-lasting benefits in ageing rats: an integrative analysis

  • Keywords:

    Medicine, Health and Life Sciences
    Metabolism; Immflamation; Microbiota

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