Repositori URV

Identificador: TDX:1150

Handle: https://hdl.handle.net/20.500.11797/TDX1150

Autors:
Barrio Torrell, Francisco José

Resum:
AIM To assess the effectiveness of an active Catalan primary care lifestyle intervention in preventing type 2 diabetes within a high-risk Mediterranean population. METHODS A cross-sectional screening study followed by a prospective cohort study. White-European individuals without diabetes (45–75 years) were screened using the Finnish Diabetes Risk Score (FINDRISC) and a subsequent 2 h OGTT. Where feasible, high-risk individuals who were identified were allocated sequentially to standard care or intensive lifestyle intervention (group-based or individual-level). RESULTS 2,054 individuals were screened by the FINDRISC and 1,192 received an OGTT. Of these, 552 accepted the lifestyle intervention (219 standard care and 333 intensive intervention–230 group-level and 103 individual-level). Diabetes was diagnosed in 124 individuals (28.8% standard care group and 18.3% intensive intervention group). Relative risk reduction was 36.5% (p<0.005) after 4.2-year median follow-up. CONCLUSION Intensive lifestyle intervention in a primary care setting substantially reduces diabetes incidence among high-risk individuals.