Prevenció de la diabetis tipus 2 en atenció primària. Estudi del perfil de risc a Europa, anàlisi d'una intervenció sobre l'estil de vida a Catalunya i ressenya de la seva contribució internacional

Identificador:  TDX:3159

Handle: https://hdl.handle.net/20.500.11797/TDX3159

Autors:  Cos Claramunt, Francesc Xavier

Resum:
Diabetes is a high-impact disease despite having theoretically effective predictive tools and prevention programs. The objectives of this thesis are to evaluate the performance of the FINDRISC scale in the European population; the feasibility and effectiveness of a lifestyle intervention program and, finally, to include it as an international reference. A cross-sectional screening study derived from the European DE-PLAN project, a multicenter cohort study (DE-PLANCAT) and its joint contribution to the Berlin Declaration are presented. The prevalence of glucose disorders (1621 men / 2483 women) was compared according to the risk interval of the FINDRISC scale. Scores between 15-19 corresponded to prevalences of 50-60% (20-30%, diabetes). With values > 20 it increased to 80% (50%, diabetes). Intensive lifestyle intervention DE-PLAN-CAT was feasible (n = 333) in primary care for 4.2 years with a significant reduction in the incidence of diabetes compared to the intervention group (n = 219) standard (4.6 / 7.2 cases / 100 people / year; RRR = 36%) and this program achieved a clear international dissemination. Therefore, FINDRISC performs well as a screening tool and subsequent intensive intervention is not only feasible but reduces the incidence of diabetes in people at risk. The contribution to the Berlin Declaration is a formal proposal at European level.