Design, synthesis and binding studies of calix(4)pyrrole based receptors suitable for ion-pair complexation and n-oxide recognition. Synthesis of resorcin(4) arene derivatives as potential ligands for supramolecular catalysis

Identifier:  TDX:1114

Handle: https://hdl.handle.net/20.500.11797/TDX1114

Authors:  Ciardi, Moira

Abstract:
The work developed during the PhD thesis deals mainly with the design and synthesis ofSupramolecular Hosts. In particular, we present new aryl-extended calix[4]pyrroleswith two or four phosphonate groups as heteroditopic receptors for the complexation of ion-pairs and that result important for the extraction of salts and for the transportof ions through membranes. Likewise, derivativesofcalix[4]pyrroles have been prepared for the selective inclusionofN-oxides in high energy conformation.The importance of the inclusion has been demonstrated by the change of the reactivity of the N-oxide in reactions in which it is commonly used as co-catalyst. Finally, we present derivatives ofresorcin[4]arenes with ethyl groups at the lower rim of thereceptor and a mobile wall in the upper rim as potential ligands for Supramolecular catalysis.