Transfer of chirality in new supramolecular complexes as design principle for future asymmetric catalysts

Identificador:  TDX:955

Handle: https://hdl.handle.net/20.500.11797/TDX955

Autores:  Degenbeck, Helmut

Resumen:
During the course of the thesis libraries of chiral (1,2)-diamines and prochiral 2,2’-biphenol derivatives were synthesised. The transfer of chirality from the diamine to the biphenol moiety mediated either by hydrogen bonding or coordination to a metal centre (ZnII, CuII) was demonstrated by CD (circular dicroism). The behaviour in solution of the hydrogen bonded complexes was investigated by NMR spectroscopy, UV-vis and ITC titrations (determination of association constants. The determination of absolute configurations of the ZnII complexes was achieved by X-ray structure determination and CD analyses both on the experimental and theoretical level. Last but not least, a new potentially catalytic phosphane ligand was derived from a dynamically racemic 2,2’-biphenol derivative.