EVALUATION OF THE IMPLEMENTATION OF AN ARTIFICIAL INSEMINATION WITH HUSBAND'S SEMEN PROGRAM AT JOAN XXIII UNIVERSITY HOSPITAL OF TARRAGONA

Identifier:  TFG:109

Handle: https://hdl.handle.net/20.500.11797/TFG109

Authors:  Bellés Aparicio, Carlos

Abstract:
Artificial insemination with husband’s semen (AIH) is a reproductive technique that involves the deposit of semen, indicted in the laboratory by techniques to improve their quality (swim-up), into the female genital tract carried out with an intrauterine insemination after having conducted a controlled ovarian stimulation. In this study, the effectiveness of the AIH program established in the Joan XXIII University Hospital since 2008 was evaluated using a sample of 51 couples. Each of the couples was subjected to a number of insemination cycles; until they achieved pregnancy, until abandonment or until the end of the maximum allowed number of cycles. Anthropological, biochemical and clinical analysis was done with all the couples, mainly based on semen quality pre and post capacitation. Then, a statistical study was performed by correlating different factors that might alter the pregnancy success. Our results show that a smaller amount of triacylglycerol’s in women is statistically associated with a greater likelihood of pregnancy (p=0.035). There has been a statistical significance between the increased percentage of post capacitation type a spermatozoa associated with an increased likelihood of a positive pregnancy (p=0.031). The fact of the decreasing in likelihood of pregnancy when exceed the fourth insemination cycle was corroborated (p=0.014). From the obtained results, we can conclude that improving some aspects in males and females using different treatments could improve the effectiveness of the technique and therefore have more chance of reaching our objective, the pregnancy.