Lipoprotein index by nuclear magnetic resonance and insulin sensitivity

Identifier:  TFG:4956

Handle: https://hdl.handle.net/20.500.11797/TFG4956

Authors:  Martín Pérez, Jose Andrés

Abstract:
Dyslipidemia is an alteration in both quantity and quality of lipids and lipoproteins that trigger cardiovascular events. These patients have atherogenic dyslipidemia which is characterized by increased triglycerides, normal LDLc transported by an increased number of small LDL particles and low HDLc. Insulin resistance is the main trigger for atherogenic dyslipidemia and is currently evaluated using the HOMA index. Lipid profile is routinely examined, which is not the case for insulin sensitivity, and that insulin resistance causes qualitative and quantitative changes in lipoprotein profile, we hypothesized that monitoring lipid profile by MRI would allow detection of signs of insulin resistance.