Polymeric replicas for biomedical applications and cell support

Identifier:  TFG:5723

Handle: https://hdl.handle.net/20.500.11797/TFG5723

Authors:  Fuentes Font, Xènia

Abstract:
Porous silicon has been used to work as a template with the aim to obtain polymeric surfaces to use them as a support for cell culture. Microporous silicon samples, fabricated by electrochemical anodization process, were chemically modified via vapor deposition using a hydrophobic self-assembled monolayer to facilitate the peel-off of the polymers to obtain the corresponding replicas. We performed polymeric surface salinization by 3-aminopropyl-triethoxysilane with glutaraldehyde followed by protein immobilization using collagen-type-I. Morphological characterization of porous silicon substrates was carried out by Environmental Scanning Electron Microscope, contact angle technique was used to evaluate the functionalization and modification of polymeric replicas.