Desarrollo de un método UHPLC-MS/MS para la determinación de biomarcadores de exposición a contaminantes atmosféricos en orina

Entity: Universitat Rovira i Virgili (URV)

Confidenciality: No

Education area(s): Tècniques Cromatogràfiques Aplicades

APS: No

Title in different languages: Development of a UHPLC-MS/MS method for the determination of biomarkers of exposure to air pollutants in urine.

Abstract: The objective of this master's thesis is to contribute to the determination of biomarkers derived from atmospheric pollutants. An analytical method has been developed for the identification of biomarkers of exposure to air pollutants in urine samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS). This analytical method has allowed the identification of 12 biomarkers, including 8 biomarkers of exposure to environmental contaminants of the BTEX family (benzene, toluene, ethylbenzene and xylenes), 3 biomarkers derived from polycyclic aromatic hydrocarbons (PAHs) and one hydrocarbon derivative. chlorinated.

Subject: Química analítica

Academic year: 2022-2023

Language: spa

Work's public defense date: 2023-06-28

Subject areas: Chemistry

Student: Esteban Miranda, Andrés

Department: Química Analítica i Química Orgànica

Creation date in repository: 2024-03-01

Keywords: UHPLC-MS/MS, exposure biomarkers, atmospheric pollutants

Title in original language: Desarrollo de un método UHPLC-MS/MS para la determinación de biomarcadores de exposición a contaminantes atmosféricos en orina

Access Rights: info:eu-repo/semantics/openAccess

Project director: Ramírez González, Noelia