Metabolomic profile of healthy dietary patterns associated with frailty in adult humans

Entity: Universitat Rovira i Virgili (URV)

Confidenciality: Si

Education area(s): Nutrició i Metabolisme

APS: No

Title in different languages: Perfil metabolòmic de patrons dietètics saludables associats amb la fragilitat en adults humans

Abstract: Frailty is a condition characterized by reduced physical reserves, increasing vulnerability to adverse health outcomes. With the rise in global life expectancy, it has become a significant public health concern. Healthy dietary patterns, such as the Mediterranean Diet, are associated with a reduced risk of frailty, potentially mediated by specific metabolic signatures. This study has two primary objectives: (1) to conduct a systematic review of existing research on the role of metabolites in the relationship between dietary patterns and frailty, and (2) to describe the baseline characteristics of the NUTRIFRAIL cohort. The results suggest that adherence to healthy diets is inversely associated with frailty and that metabolic signatures of these dietary patterns mediate the relationship between healthy dietary patterns and frailty.

Subject: Metabolòmica

Academic year: 2023-2024

Language: en

Work's public defense date: 2024-10-10

Subject areas: Health sciences

Student: Puzankova, Evgeniia

Department: Bioquímica i Biotecnologia

Creation date in repository: 2025-05-27

TFM credits: 18

Keywords: Metabolomics, metabolic profile, matabolic signatures, frailty, dietary pattern

Title in original language: Metabolomic profile of healthy dietary patterns associated with frailty in adult humans

Access Rights: info:eu-repo/semantics/openAccess

Project director: Rabassa Bonet, montserrat