Treballs Fi de MàsterBioquímica i Biotecnologia

Effects of berberine supplementation on lipid profile in adults with metabolic disorders: a systematic review and meta-analysis

  • Identification data

    Identifier:  TFM:2514
    Handle: https://hdl.handle.net/20.500.11797/TFM2514
    Authors:  Sempértegui Moreira, Andrea Valeria
    Abstract:
    This study evaluated the effects of berberine supplementation on the lipid profile of adults with metabolic disorders through a systematic review and meta-analysis of randomized clinical trials. Six studies were included, revealing a significant reduction in total cholesterol but no conclusive effects on LDL-C, HDL-C, or triglycerides. Sensitivity analyses showed that, after excluding outlier studies, berberine significantly reduced LDL-C and decreased heterogeneity, whereas results regarding HDL-C and triglycerides remained null. Overall, berberine represents a promising option as an adjunct in the management of dyslipidemia.

  • Others:

    Entity: Universitat Rovira i Virgili (URV)
    Confidenciality: No
    Student: Sempértegui Moreira, Andrea Valeria
    Education area(s): Nutrició i Metabolisme
    APS: No
    Department: Bioquímica i Biotecnologia
    Creation date in repository: 2026-09-28
    Subject: Nutrició
    Academic year: 2024-2025
    Work's public defense date: 2025-09-15
    Access Rights: info:eu-repo/semantics/openAccess
    Project director: Fernandez Lopez, Jose Antonio

  • Keywords:

    Berberine
    Dyslipidemia
    Meta-analysis
    Health sciences

  • Documents:

    Memòria

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