Repositori URV

Autor segons l'article: Jordi Salas-Salvado; Rosa Sola; Gemma Godas; Josep Ribalta; Joan-Carles Vallvé; Josefa Girona; Anna Anguera; Ma Adoracion Ostos; Delia Recalde; Juliana Salazar; Muriel Caslake; Francisco Martín-Lujan; Lluis Masana

Departament: Bioquímica i Biotecnologia

Autor/s de la URV: SALAS SALVADÓ, JORGE; Rosa Sola; Gemma Godas; Josep Ribalta; Joan-Carles Vallvé; Josefa Girona; Anna Anguera; Ma Adoracion Ostos; Delia Recalde; Juliana Salazar; Muriel Caslake; Francisco Martín-Lujan; Lluis Masana

Paraules clau: polymorphism secondary prevention of cardiovascular disease Dietary fiber

Resum: BACKGROUND: New dietary strategies to reduce cardiovascular disease (CVD) risk include the addition of fiber to the diet. The effect of soluble-fiber consumption derived from Plantago ovata husk on lipid risk factors in patients with CVD is unknown. OBJECTIVE: We compared the effects of soluble fiber (P. ovata husk) with those of insoluble fiber (P. ovata seeds) on plasma lipid, lipoprotein, and apolipoprotein (apo) concentrations within a CVD secondary prevention program. DESIGN: In a randomized, crossover, controlled, single-blind design, 28 men with CVD (myocardial infarction or stable angina) and an LDL-cholesterol concentration </=3.35 mmol/L consumed for 8 wk, under controlled conditions, a low-saturated-fat diet supplemented with 10.5 g P. ovata husk/d or 10.5 g P. ovata seeds/d. Fasting plasma lipid concentrations and polymorphisms of genes involved in lipid metabolism, such as apo A-IV, apo E, and fatty acid-binding protein, were measured. RESULTS: Plasma triacylglycerol decreased (6.7%; P < 0.02), the ratio of apo B 100 to apo A-I decreased (4.7%; P < 0.02), and apo A-I increased (4.3%; P < 0.01) in the P. ovata husk consumers. Compared with the intake of insoluble fiber, the intake of P. ovata husk increased HDL-cholesterol concentrations by 6.7% (P = 0.006) and decreased the ratio of total to HDL cholesterol and of LDL to HDL cholesterol by 10.6% (P = 0.002) and 14.2% (P = 0.003), respectively. CONCLUSION: In the secondary prevention of CVD, P. ovata husk intake induces a more beneficial effect on the cardiovascular lipid risk-factor profile than does an equivalent intake of insoluble fiber.

Grup de recerca: Alimentació, Nutrició, Creixement i Salut Mental

Àrees temàtiques: Biochemistry and technology Bioquímica y tecnología Bioquímica i biotecnologia

Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0002-9165

Identificador de l'autor: N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D

Data d'alta del registre: 2016-06-13

Pàgina final: 1163

Volum de revista: 85

Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion

Enllaç font original: https://academic.oup.com/ajcn/article/85/4/1157/4648880?searchresult=1

URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/

DOI de l'article: 10.1093/ajcn/85.4.1157

Entitat: Universitat Rovira i Virgili

Any de publicació de la revista: 2007

Pàgina inicial: 1157

Tipus de publicació: Article Artículo Article