Virulence and experimental treatment of Trichoderma longibrachiatum

Identificador:  PC:1831

Handle: https://hdl.handle.net/20.500.11797/PC1831

Autors:  Katihuska Paredes; Javier Capilla; Emilio Mayayo; Josep Guarro

Resum:
Different inocula of Trichoderma longibrachiatum were tested in a murine model, and only the highest one (1 × 107 CFU/animal) killed all of the mice at day 15 postinfection, with spleen and liver the most affected organs. The efficacies of amphotericin B deoxycholate, liposomal amphotericin B, voriconazole, and micafungin were evaluated in the same model, with very poor results. Our study demonstrated the low virulence but high resistance to antifungal compounds of this fungus.