Articles producció científica> Ciències Mèdiques Bàsiques

Virulence and experimental treatment of Trichoderma longibrachiatum, a fungus refractory to treatment

  • Identification data

    Identifier: PC:1831
    Authors:
    Katihuska ParedesJavier CapillaEmilio MayayoJosep Guarro
    Abstract:
    Different inocula of Trichoderma longibrachiatum were tested in a murine model, and only the highest one (1 × 107 CFU/animal) killed all of the mice at day 15 postinfection, with spleen and liver the most affected organs. The efficacies of amphotericin B deoxycholate, liposomal amphotericin B, voriconazole, and micafungin were evaluated in the same model, with very poor results. Our study demonstrated the low virulence but high resistance to antifungal compounds of this fungus.
  • Others:

    Author, as appears in the article.: Katihuska Paredes; Javier Capilla; Emilio Mayayo; Josep Guarro
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: PAREDES AGUILAR, KATIHUSKA VIVIANA; Javier Capilla; MAYAYO ARTAL, EMILIO MANUEL; GUARRO ARTIGAS, JOSEP
    Keywords: Trichoderma longibrachiatum Virulence fungus
    Abstract: Different inocula of Trichoderma longibrachiatum were tested in a murine model, and only the highest one (1 × 107 CFU/animal) killed all of the mice at day 15 postinfection, with spleen and liver the most affected organs. The efficacies of amphotericin B deoxycholate, liposomal amphotericin B, voriconazole, and micafungin were evaluated in the same model, with very poor results. Our study demonstrated the low virulence but high resistance to antifungal compounds of this fungus.
    Research group: Unitat de Micologia i Microbiologia Ambiental
    Thematic Areas: Ciències de la salut Ciencias de la salud Health sciences
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0066-4804
    Record's date: 2016-09-13
    Last page: 5032
    Journal volume: 60
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://aac.asm.org/content/60/8/5029
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1128/AAC.00373-16
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2016
    First page: 5029
    Publication Type: Article Artículo Article
  • Keywords:

    Fongs patògens
    Trichoderma longibrachiatum
    Virulence
    fungus
    Ciències de la salut
    Ciencias de la salud
    Health sciences
    0066-4804
  • Documents:

  • Cerca a google

    Search to google scholar