Articles producció científicaCiències Mèdiques Bàsiques

Virulence and experimental treatment of Trichoderma longibrachiatum, a fungus refractory to treatment

  • Identification data

    Identifier:  PC:1831
    Handle: https://hdl.handle.net/20.500.11797/PC1831
    Authors:  Katihuska Paredes; Javier Capilla; Emilio Mayayo; Josep Guarro
    Abstract:
    Different inocula of Trichoderma longibrachiatum were tested in a murine model, and only the highest one (1 × 107 CFU/animal) killed all of the mice at day 15 postinfection, with spleen and liver the most affected organs. The efficacies of amphotericin B deoxycholate, liposomal amphotericin B, voriconazole, and micafungin were evaluated in the same model, with very poor results. Our study demonstrated the low virulence but high resistance to antifungal compounds of this fungus.

  • Others:

    Link to the original source: https://aac.asm.org/content/60/8/5029
    Article's DOI: 10.1128/AAC.00373-16
    Journal publication year: 2016
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/acceptedVersion
    Record's date: 2016-09-13
    First page: 5029
    URV's Author/s: PAREDES AGUILAR, KATIHUSKA VIVIANA; Javier Capilla; MAYAYO ARTAL, EMILIO MANUEL; GUARRO ARTIGAS, JOSEP
    Department: Ciències Mèdiques Bàsiques
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Article
    Last page: 5032
    ISSN: 0066-4804
    Author, as appears in the article.: Katihuska Paredes; Javier Capilla; Emilio Mayayo; Josep Guarro
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Journal volume: 60
    Research group: Unitat de Micologia i Microbiologia Ambiental
    Thematic Areas: Health sciences

  • Keywords:

    Trichoderma longibrachiatum
    Virulence
    fungus

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