Autor segons l'article: Borrull, F. ; Prosen, H; Fontanals, N. ; Marcé, R.M.
Departament: Química Analítica i Química Orgànica
Autor/s de la URV: BORRULL BALLARÍN, FRANCESC; Prosen, H; Fontanals, N. ; MARCÉ RECASENS, ROSA MARIA
Paraules clau: cathinones drugs of abuse Environmental water samples
Resum: A method based on liquid chromatography with electrospray ionization high-resolution mass spectrometry (Exactive Orbitrap) combined with solid-phase extraction using a strong cationic exchange mixed-mode sorbent has been developed for the determination of seven drugs of abuse, including two synthetic cathinones, as well as some of their metabolites in environmental water samples. The method provides low detection limits and a high confirmation power thanks to the diagnostic and two fragment ions monitored for each compound in high-resolution mass spectrometry, providing six identification points for each analyte. The clean-up step based on methanol in the extraction step adequately decreased the matrix effect, mainly for river and effluent water, and provided suitable process efficiency. Method detection and quantitation limits for environmental waters were at low nanogram per liter. The method was applied to analyze the samples of influent and effluent wastewater, as well as surface water. Codeine, methadone, and its metabolite were determined in all samples of wastewater and the metabolite of cocaine, benzoylecgonine, was found at the highest concentration.
Grup de recerca: Grup de Cromatografia. Aplicacions Mediambientals
Àrees temàtiques: Química Química Chemistry
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1615-9306
Identificador de l'autor: 0000-0003-2718-9336; ; ; 0000-0002-5667-2899
Data d'alta del registre: 2018-02-28
Pàgina final: 3631
Volum de revista: 40
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://onlinelibrary.wiley.com/doi/abs/10.1002/jssc.201700287
Programa de finançament: plan; Excelencia; CTQ2014-52617-P altres; Slovenian Research Agency; P1-0153
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1002/jssc.201700287
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2017
Pàgina inicial: 3621
Tipus de publicació: Article Artículo Article