Autor segons l'article: Siqueira JPZ, Sutton DA, Gené J, García D, Wiederhold N, Guarro J.
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: García Sánchez, Dania / Gené Díaz, Josepa / Guarro Artigas, Josep / ZEN SIQUEIRA, JOAO PAULO
Paraules clau: Taxonomy Phylogenetic analysis Eurotium Aspergillus Antifungal susceptibility
Resum: The diversity of Aspergillus species in clinical samples is continuously increasing. Species under the former name Eurotium, currently accommodated in section Aspergillus of the genus Aspergillus, are xerophilic fungi widely found in the human environment and able to grow on substrates with low water activity. However, their prevalence in the clinical setting is poorly known. We have studied the presence of these species in a set of clinical samples from the United States using a multilocus sequence analysis based on the internal transcribed spacer (ITS) region of the rRNA, and fragments of the genes β-tubulin (BenA), calmodulin (CaM), and polymerase II second largest subunit (RPB2). A total of 25 isolates were studied and identified as follows: A. montevidensis (44%), A. chevalieri (36%), A. pseudoglaucus (8%), and A. costiformis (4%). A new species Aspergillus microperforatus is also proposed, which represented 8% of the isolates studied and is characterized by uniseriate conidial heads, subglobose to pyriform vesicles, rough conidia, globose to subglobose cleistothecia, and lenticular and smooth ascospores. The in vitro antifungal activity of eight clinically available antifungals was also determined against these isolates, with the echinocandins and posaconazole having the most potent activity.
Àrees temàtiques: Zootecnia / recursos pesqueiros Veterinary sciences Veterinary (miscellaneous) Saúde coletiva Química Odontología Mycology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Infectious diseases Geografía General veterinary Farmacia Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 13693786
Adreça de correu electrònic de l'autor: dania.garcias@urv.cat josepa.gene@urv.cat
Identificador de l'autor: 0000-0003-2397-1646 0000-0001-6195-9299
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://academic.oup.com/mmy/article/56/5/541/4372452
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Medical Mycology. 56 (5): 541-550
Referència de l'ítem segons les normes APA: Siqueira JPZ, Sutton DA, Gené J, García D, Wiederhold N, Guarro J. (2018). Species of Aspergillus section Aspergillus from clinical samples in the United States. Medical Mycology, 56(5), 541-550. DOI: 10.1093/mmy/myx085
DOI de l'article: 10.1093/mmy/myx085
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2018
Tipus de publicació: Journal Publications