Autor segons l'article: Bravo N; Peralta S; Grimalt J; Martínez M; Rovira J; Schuhmacher M
Departament: Ciències Mèdiques Bàsiques Enginyeria Química
Autor/s de la URV: Martínez Rodríguez, María Ángeles / Rovira Solano, Joaquim / Schuhmacher Ansuategui, Marta
Paraules clau: Reproducibility of results Pyrethroids Pregnant women Pregnancy Pesticides Organophosphorus pesticides Organophosphorus compounds Organophosphates Maternal exposure Humans Human biomonitoring Female Environmental exposure Agriculture pregnant women organophosphorus pesticides human biomonitoring agriculture
Resum: © 2019 Elsevier Inc. The burden of organophosphate (OP) pesticides in pregnant women from Tarragona (n = 157), a Mediterranean area of intense agricultural activity, has been assessed from the study of hydroxylated organic metabolites in urine samples in the three trimesters of pregnancy. 2-Diethylamino-6-methylpyrimidin-4-ol (DEAMPY), a metabolite of pirimiphos, was the compound found in higher concentration, medians 0.66–2.8 μg/g creatinine. 4-Nitrophenol (PNP), a metabolite of parathion, medians 0.24–0.41 μg/g creatinine, was the second most abundant compound. 2-Isopropyl-6-methyl-4-pyrimidol (IMPY), a metabolite of diazinon, was also present but in lower concentrations. Except for DEAMPY, the concentrations found in this cohort were lower than those reported in studies from other countries. Intraclass correlation coefficients (ICCs) were calculated for the compounds found in more than the 35% of the samples, the reliability between trimesters was poor (<0.40) to fair (0.40–0.60). Statistically significant differences were observed for the creatinine adjusted concentrations of the most abundant OP metabolites in these trimesters when examined with the Wilcoxon signed rank test for paired data. In general, no association was found between urinary OP metabolites and most demographic and lifestyle predictors. However, a positive significant association was observed for women with vegetarian diet and for women of higher economic status and eventual consumption of organic food which showed higher PNP concentrations. These results suggest that higher fruit and vegetable consumption may involve higher OP pesticide ingestion but the overall association was weak.
Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Public, environmental & occupational health Public health, environmental and occupational health Psicología Planejamento urbano e regional / demografia Odontología Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine General environmental science Farmacia Environmental sciences Environmental science (miscellaneous) Environmental science (all) Ensino Engenharias iii Engenharias ii Engenharias i Enfermagem Educação física Direito Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade Biochemistry Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0013-9351
Adreça de correu electrònic de l'autor: mangeles.martinez@urv.cat joaquim.rovira@urv.cat marta.schuhmacher@urv.cat
Identificador de l'autor: 0000-0001-8595-3772 0000-0003-4399-6138 0000-0003-4381-2490
Data d'alta del registre: 2024-07-27
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/abs/pii/S001393511930800X?via%3Dihub
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Environmental Research. 182 (109003): 109003-
Referència de l'ítem segons les normes APA: Bravo N; Peralta S; Grimalt J; Martínez M; Rovira J; Schuhmacher M (2020). Organophosphate metabolite concentrations in maternal urine during pregnancy. Environmental Research, 182(109003), 109003-. DOI: 10.1016/j.envres.2019.109003
DOI de l'article: 10.1016/j.envres.2019.109003
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2020
Tipus de publicació: Journal Publications