Articles producció científicaBioquímica i Biotecnologia

The effects of different quantities and qualities of protein intake in people with diabetes mellitus

  • Dades identificatives

    Identificador:  imarina:6090598
    Autors:  Pfeiffer, Andreas F H; Pedersen, Eva; Schwab, Ursula; Riserus, Ulf; Aas, Anne-Marie; Uusitupa, Matti; Thanopoulou, Anastasia; Kendall, Cyril; Sievenpiper, John L; Kahleova, Hana; Rahelic, Dario; Salas-Salvado, Jordi; Gebauer, Stephanie; Hermansen, Kjeld
    Resum:
    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The recommended amount and quality of protein in diets of diabetic patients are highly controversial. In order to provide evidence-based information, the Diabetes Nutrition Study Group (DNSG) used a grading procedure used for quality of evidence and strength of recommendations (GRADE). A protein intake of 10% to 20% of energy intake (E%) or about 0.8 to 1.3 g/kg body weight in people below 65 years of age, and 15% to 20% of E% in people above 65 years of age appeared safe in weight-stable conditions. There were no intervention studies addressing metabolic effects, mortality, or cardiovascular events over prolonged periods. Body weight is closely linked to metabolic control and high protein diets are often recommended. Weight-loss diets that include 23% to 32% of E% as protein for up to one year reduced blood pressure and body weight slightly but significantly more than lower protein diets, whereas blood lipids, fasting blood glucose, and HbA1c improved similarly with higher or lower protein intakes in participants with a glomerular filtration rate (GFR) >60 mL/min/1.73 m2 . Patients with a GFR <60 mL/min/1.73 m2 did not show a faster decline of GFR or kidney function with protein intakes around 0.8 g/kg body weight as compared with lower intakes, thereby arguing against a restriction. The effects of protein intake on diabetic eye or nerve disease have not been reported. There are a number of studies that have compared different types of animal proteins (milk, chicken, beef, pork, and fish) or compared animal with plant protein in diabetic patients and have reported a greater reduction of serum cholesterol with plant protein. In summary, the suggested range of protein intake appears to be safe and can be adapted a
  • Altres:

    Autor segons l'article: Pfeiffer, Andreas F H; Pedersen, Eva; Schwab, Ursula; Riserus, Ulf; Aas, Anne-Marie; Uusitupa, Matti; Thanopoulou, Anastasia; Kendall, Cyril; Sievenpiper, John L; Kahleova, Hana; Rahelic, Dario; Salas-Salvado, Jordi; Gebauer, Stephanie; Hermansen, Kjeld
    Departament: Bioquímica i Biotecnologia
    Autor/s de la URV: Salas Salvadó, Jorge
    Paraules clau: Weight-loss; Weight loss; Type-2; Type 2 diabetes; Randomized controlled-trial; Protein intake; Plant protein; Middle aged; Metaanalysis; Management; Male; Low-fat diet; Individuals; Hypocaloric diet; Humans; Hemoglobin a1c protein, human; Glycated hemoglobin a; Glycated hemoglobin; Glomerular filtration rate; Female; Energy intake; Dietary proteins; Dietary carbohydrate-restriction; Diet, protein-restricted; Diet, high-protein; Diabetes mellitus, type 2; Body-weight; Blood-pressure; Blood pressure; Animal protein; Adult; type 2 diabetes; protein intake; plant protein; hypocaloric diet; animal protein
    Resum: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The recommended amount and quality of protein in diets of diabetic patients are highly controversial. In order to provide evidence-based information, the Diabetes Nutrition Study Group (DNSG) used a grading procedure used for quality of evidence and strength of recommendations (GRADE). A protein intake of 10% to 20% of energy intake (E%) or about 0.8 to 1.3 g/kg body weight in people below 65 years of age, and 15% to 20% of E% in people above 65 years of age appeared safe in weight-stable conditions. There were no intervention studies addressing metabolic effects, mortality, or cardiovascular events over prolonged periods. Body weight is closely linked to metabolic control and high protein diets are often recommended. Weight-loss diets that include 23% to 32% of E% as protein for up to one year reduced blood pressure and body weight slightly but significantly more than lower protein diets, whereas blood lipids, fasting blood glucose, and HbA1c improved similarly with higher or lower protein intakes in participants with a glomerular filtration rate (GFR) >60 mL/min/1.73 m2 . Patients with a GFR <60 mL/min/1.73 m2 did not show a faster decline of GFR or kidney function with protein intakes around 0.8 g/kg body weight as compared with lower intakes, thereby arguing against a restriction. The effects of protein intake on diabetic eye or nerve disease have not been reported. There are a number of studies that have compared different types of animal proteins (milk, chicken, beef, pork, and fish) or compared animal with plant protein in diabetic patients and have reported a greater reduction of serum cholesterol with plant protein. In summary, the suggested range of protein intake appears to be safe and can be adapted according to personal dietary preferences.
    Àrees temàtiques: Zootecnia / recursos pesqueiros; Saúde coletiva; Química; Psicología; Planejamento urbano e regional / demografia; Nutrition and dietetics; Nutrition & dietetics; Nutrição; Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Interdisciplinar; Food science; Farmacia; Engenharias iv; Engenharias ii; Enfermagem; Educação física; Economia; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências agrárias i; Ciência de alimentos; Biotecnología
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 20726643
    Adreça de correu electrònic de l'autor: jordi.salas@urv.cat
    Data d'alta del registre: 2025-02-18
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.mdpi.com/2072-6643/12/2/365
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Nutrients. 12 (2): 365-
    Referència de l'ítem segons les normes APA: Pfeiffer, Andreas F H; Pedersen, Eva; Schwab, Ursula; Riserus, Ulf; Aas, Anne-Marie; Uusitupa, Matti; Thanopoulou, Anastasia; Kendall, Cyril; Sievenpi (2020). The effects of different quantities and qualities of protein intake in people with diabetes mellitus. Nutrients, 12(2), 365-. DOI: 10.3390/nu12020365
    DOI de l'article: 10.3390/nu12020365
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2020
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Weight-loss
    Weight loss
    Type-2
    Type 2 diabetes
    Randomized controlled-trial
    Protein intake
    Plant protein
    Middle aged
    Metaanalysis
    Management
    Male
    Low-fat diet
    Individuals
    Hypocaloric diet
    Humans
    Hemoglobin a1c protein, human
    Glycated hemoglobin a
    Glycated hemoglobin
    Glomerular filtration rate
    Female
    Energy intake
    Dietary proteins
    Dietary carbohydrate-restriction
    Diet, protein-restricted
    Diet, high-protein
    Diabetes mellitus, type 2
    Body-weight
    Blood-pressure
    Blood pressure
    Animal protein
    Adult
    type 2 diabetes
    protein intake
    plant protein
    hypocaloric diet
    animal protein
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science
    Farmacia
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
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